Paclitaxel EP Impurity G

Name: Paclitaxel EP Impurity G
Brand: Vaqora Chemicals
SKU: VQ-023452

About Paclitaxel EP Impurity G

Listed under CAS 78432-77-6, Paclitaxel EP Impurity G is a pharmacopeial impurity of Paclitaxel available from Vaqora Chemicals. With the molecular formula C45H49NO13, it has a molar mass of 811.9 g/mol. It is also known as Paclitaxel Impurity - G or Paclitaxel - Impurity G.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 15 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Paclitaxel, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Paclitaxel

View every impurity, metabolite and intermediate we list for Paclitaxel.

Paclitaxel impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Paclitaxel EP Impurity G
Catalogue No.	VQ-023452
CAS Number	78432-77-6
IUPAC name	[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9,12-trihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
Molecular formula	C₄₅H₄₉NO₁₃
Molecular weight	811.9 g/mol
Exact mass	811.3204
Grade	Reference Standard
HSN code	38229090
InChIKey	TYLVGQKNNUHXIP-MHHARFCSSA-N
SMILES	CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)O
PubChem CID	155831

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	5 / 13
TPSA	215 Å²
Synonyms	Paclitaxel Impurity - G, Paclitaxel - Impurity G, 10-Deacetyltaxol, 10-Deacetylpaclitaxel, 10-deacetyl-paclitaxel, 10-Deacetyl-7-epitaxol, 10-Desacetyl Paclitaxel, 10-Desacetyltaxol, Deacetyltaxol10-Deacetyltaxol, 10-deacetyl taxol, 10-Deacetyl-7-epi-taxol, 10-Desacetylpaclitaxel

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H336May cause drowsiness or dizziness
H340May cause genetic defects
H341Suspected of causing genetic defects
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life

Precautionary statements: P203, P233, P260, P261, P264, P264 + P265, P270, P271, P272, P273, P280, P284, P301 + P316, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P318, P319, P321, P330, P332 + P317, P333 + P317, P342 + P316

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Paclitaxel EP Impurity G?

The CAS Registry Number of Paclitaxel EP Impurity G is 78432-77-6. It is also known as Paclitaxel Impurity - G, Paclitaxel - Impurity G, 10-Deacetyltaxol.

What is the molecular formula and molecular weight of Paclitaxel EP Impurity G?

Paclitaxel EP Impurity G has the molecular formula C45H49NO13 and a molecular weight of 811.9 g/mol.

What is Paclitaxel EP Impurity G used for?

Paclitaxel EP Impurity G is supplied as a characterised reference material related to Paclitaxel. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Paclitaxel EP Impurity G can I order?

We supply Paclitaxel EP Impurity G in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Paclitaxel EP Impurity G?

Yes. Every lot of Paclitaxel EP Impurity G is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Paclitaxel EP Impurity G be shipped internationally?

Yes. Paclitaxel EP Impurity G is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.