(R)-4-Nitrothalidomide

Name: (R)-4-Nitrothalidomide
Brand: Vaqora Chemicals
SKU: VQ-041551

About (R)-4-Nitrothalidomide

Listed under CAS 202271-81-6, (R)-4-Nitrothalidomide is an impurity of Thalidomide available from Vaqora Chemicals. The compound has the formula C13H9N3O6, corresponding to a molecular weight of 303.23 g/mol. Systematically, it is named 2-[(3R)-2,6-dioxopiperidin-3-yl]-4-nitroisoindole-1,3-dione. It is also known as 4-Nitrothalidomide, (+)- or 4-Nitrothalidomide, (R)-.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Thalidomide to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (R)-4-Nitrothalidomide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Thalidomide

View every impurity, metabolite and intermediate we list for Thalidomide.

Thalidomide impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-4-Nitrothalidomide
Catalogue No.	VQ-041551
CAS Number	202271-81-6
IUPAC name	2-[(3R)-2,6-dioxopiperidin-3-yl]-4-nitroisoindole-1,3-dione
Molecular formula	C₁₃H₉N₃O₆
Molecular weight	303.23 g/mol
Exact mass	303.0491
Grade	Reference Standard
HSN code	38229090
InChIKey	KVRCAGKHAZRSQX-MRVPVSSYSA-N
SMILES	C1CC(=O)NC(=O)[C@@H]1N2C(=O)C3=C(C2=O)C(=CC=C3)[N+](=O)[O-]
PubChem CID	20581734

Physical properties
Physical form	Solid
LogP (XLogP3)	0.2
H-bond donors / acceptors	1 / 6
TPSA	129 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-4-Nitrothalidomide?

The CAS Registry Number of (R)-4-Nitrothalidomide is 202271-81-6. It is also known as 4-Nitrothalidomide, (+)-, 4-Nitrothalidomide, (R)-, 1H-Isoindole-1,3(2H)-dione, 2-((3R)-2,6-dioxo-3-piperidinyl)-4-nitro-.

What is the molecular formula and molecular weight of (R)-4-Nitrothalidomide?

(R)-4-Nitrothalidomide has the molecular formula C13H9N3O6 and a molecular weight of 303.23 g/mol. Its IUPAC name is 2-[(3R)-2,6-dioxopiperidin-3-yl]-4-nitroisoindole-1,3-dione.

What is (R)-4-Nitrothalidomide used for?

(R)-4-Nitrothalidomide is supplied as a characterised reference material related to Thalidomide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-4-Nitrothalidomide can I order?

We supply (R)-4-Nitrothalidomide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-4-Nitrothalidomide?

Yes. Every lot of (R)-4-Nitrothalidomide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-4-Nitrothalidomide be shipped internationally?

Yes. We export (R)-4-Nitrothalidomide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.