3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyri… 943320-60-3

Name: 3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine
Brand: Vaqora Chemicals
SKU: VQ-041555

About 3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine

3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine (CAS 943320-60-3) is an impurity of Ponatinib offered by Vaqora Chemicals. Its molecular formula is C11H13N3Si and its molecular weight is 215.33 g/mol. Systematically, it is named 2-imidazo[1,2-b]pyridazin-3-ylethynyl(trimethyl)silane.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Ponatinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ponatinib

View every impurity, metabolite and intermediate we list for Ponatinib.

Ponatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine
Catalogue No.	VQ-041555
CAS Number	943320-60-3
IUPAC name	2-imidazo[1,2-b]pyridazin-3-ylethynyl(trimethyl)silane
Molecular formula	C₁₁H₁₃N₃Si
Molecular weight	215.33 g/mol
Exact mass	215.0879
Grade	Reference Standard
HSN code	38229090
InChIKey	AUMLXDLZHWMUCA-UHFFFAOYSA-N
SMILES	C[Si](C)(C)C#CC1=CN=C2N1N=CC=C2
PubChem CID	66735569

Physical properties
Physical form	Solid
H-bond donors / acceptors	0 / 2
TPSA	30.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine?

The CAS Registry Number of 3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine is 943320-60-3. It is also known as IMidazo[1,2-b]pyridazine, 3-[2-(triMethylsilyl)ethynyl]-, Imidazo(1,2-b)pyridazine, 3-(2-(trimethylsilyl)ethynyl)-, 3-[2-(trimethylsilyl)ethynyl]-Imidazo[1,2-b]pyridazine.

What is the molecular formula and molecular weight of 3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine?

3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine has the molecular formula C11H13N3Si and a molecular weight of 215.33 g/mol. Its IUPAC name is 2-imidazo[1,2-b]pyridazin-3-ylethynyl(trimethyl)silane.

What is 3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine used for?

3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine is supplied as a characterised reference material related to Ponatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine can I order?

We supply 3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine?

Yes. Every lot of 3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine be shipped internationally?

Yes. We export 3-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.