Ramipril EP Impurity K

Name: Ramipril EP Impurity K
Brand: Vaqora Chemicals
SKU: VQ-006634

About Ramipril EP Impurity K

Ramipril EP Impurity K is a pharmacopeial impurity of Ramipril carrying the CAS registry number 108736-10-3. The compound has the formula C21H26N2O4, corresponding to a molecular weight of 370.4 g/mol. The IUPAC name is (2S)-2-[(2S,6S,8S,11S)-11-methyl-9,12-dioxo-1,10-diazatricyclo[6.4.0.02,6]dodecan-10-yl]-4-phenylbutanoic acid. Alternative names: Ramiprilat Diketopiperazine and Ramipril Diketopiperazine Acid.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Ramipril to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ramipril EP Impurity K in 10 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Ramipril

View every impurity, metabolite and intermediate we list for Ramipril.

Ramipril impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ramipril EP Impurity K
Catalogue No.	VQ-006634
CAS Number	108736-10-3
IUPAC name	(2S)-2-[(2S,6S,8S,11S)-11-methyl-9,12-dioxo-1,10-diazatricyclo[6.4.0.02,6]dodecan-10-yl]-4-phenylbutanoic acid
Molecular formula	C₂₁H₂₆N₂O₄
Molecular weight	370.4 g/mol
Exact mass	370.1893
Grade	Reference Standard
HSN code	38229090
InChIKey	DZRWPCCIYKIPJW-HILJTLORSA-N
SMILES	C[C@H]1C(=O)N2[C@H]3CCC[C@H]3C[C@H]2C(=O)N1[C@@H](CCC4=CC=CC=C4)C(=O)O
PubChem CID	69267073

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	1 / 4
TPSA	77.9 Å²

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H360May damage fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ramipril EP Impurity K?

The CAS Registry Number of Ramipril EP Impurity K is 108736-10-3. It is also known as 2-(5-Methyl-4,7-dioxo-decahydro-3b,6-diaza-cyclopenta[a]inden-6-yl)-4-phenyl-butyric acid, Ramiprilat Diketopiperazine, Ramipril Diketopiperazine Acid.

What is the molecular formula and molecular weight of Ramipril EP Impurity K?

Ramipril EP Impurity K has the molecular formula C21H26N2O4 and a molecular weight of 370.4 g/mol. Its IUPAC name is (2S)-2-[(2S,6S,8S,11S)-11-methyl-9,12-dioxo-1,10-diazatricyclo[6.4.0.02,6]dodecan-10-yl]-4-phenylbutanoic acid.

What is Ramipril EP Impurity K used for?

Ramipril EP Impurity K is supplied as a characterised reference material related to Ramipril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ramipril EP Impurity K can I order?

We supply Ramipril EP Impurity K in Reference Standard grade, in 10 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ramipril EP Impurity K?

Yes. Every lot of Ramipril EP Impurity K is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ramipril EP Impurity K be shipped internationally?

Yes. Ramipril EP Impurity K is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.