Rel-Sacubitril (2R,4R) Isomer

Name: Rel-Sacubitril (2R,4R) Isomer
Brand: Vaqora Chemicals
SKU: VQ-005723

About Rel-Sacubitril (2R,4R) Isomer

Vaqora Chemicals supplies Rel-Sacubitril (2R,4R) Isomer, an impurity of Sacubitril registered under CAS number 766480-48-2. Formula C24H29NO5, molecular weight 411.5 g/mol. The IUPAC name is 4-[[(2R,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid. Alternative names: (2R,4R)-Sacubitril Isomer and 2R,4R-Sacubitril.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Sacubitril impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Rel-Sacubitril (2R,4R) Isomer is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	Rel-Sacubitril (2R,4R) Isomer
Catalogue No.	VQ-005723
CAS Number	766480-48-2
Other CAS	2259708-00-2
IUPAC name	4-[[(2R,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid
Molecular formula	C₂₄H₂₉NO₅
Molecular weight	411.5 g/mol
Exact mass	411.2046
Grade	Reference Standard
HSN code	38229090
InChIKey	PYNXFZCZUAOOQC-DYESRHJHSA-N
SMILES	CCOC(=O)[C@H](C)C[C@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O
PubChem CID	9829628

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	2 / 5
TPSA	92.7 Å²
Synonyms	rel-4-Ethyl (αR,γR)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1′-biphenyl]-4-pentanoate, (2R,4R)-Sacubitril Isomer, 2R,4R-Sacubitril, (2R,4R)-Sacubitril, Sacubitril-(2R,4R)-Isomer, pound Ca pound(c), Sacubitril, (2R,4R)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rel-Sacubitril (2R,4R) Isomer?

The CAS Registry Number of Rel-Sacubitril (2R,4R) Isomer is 766480-48-2. It is also known as rel-4-Ethyl (αR,γR)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1′-biphenyl]-4-pentanoate, (2R,4R)-Sacubitril Isomer, 2R,4R-Sacubitril.

What is the molecular formula and molecular weight of Rel-Sacubitril (2R,4R) Isomer?

Rel-Sacubitril (2R,4R) Isomer has the molecular formula C24H29NO5 and a molecular weight of 411.5 g/mol. Its IUPAC name is 4-[[(2R,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid.

What is Rel-Sacubitril (2R,4R) Isomer used for?

Rel-Sacubitril (2R,4R) Isomer is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rel-Sacubitril (2R,4R) Isomer can I order?

We supply Rel-Sacubitril (2R,4R) Isomer in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rel-Sacubitril (2R,4R) Isomer?

Yes. Every lot of Rel-Sacubitril (2R,4R) Isomer is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rel-Sacubitril (2R,4R) Isomer be shipped internationally?

Yes. We export Rel-Sacubitril (2R,4R) Isomer worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.