Ribociclib hydrochloride

Name: Ribociclib hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-033527

About Ribociclib hydrochloride

Listed under CAS 1211443-80-9, Ribociclib hydrochloride is a high-purity reference standard of Ribociclib available from Vaqora Chemicals. With the molecular formula C23H31ClN8O, it has a molar mass of 471.0 g/mol. Common synonyms include Ribociclib HCl and LEE011 hydrochloride.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this Ribociclib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ribociclib hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Ribociclib

View every impurity, metabolite and intermediate we list for Ribociclib.

Ribociclib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ribociclib hydrochloride
Catalogue No.	VQ-033527
CAS Number	1211443-80-9
IUPAC name	7-cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-yl-2-pyridinyl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide;hydrochloride
Molecular formula	C₂₃H₃₁ClN₈O
Molecular weight	471 g/mol
Exact mass	470.2309
Grade	Reference Standard
HSN code	38229090
InChIKey	JZRSIQPIKASMEV-UHFFFAOYSA-N
SMILES	CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5.Cl
PubChem CID	67242274

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 7
TPSA	91.2 Å²
Synonyms	Ribociclib HCl, LEE011 hydrochloride, LEE011 (hydrochloride), EX-A1585, LEE-011 HCl salt, Ribociclib HCl salt

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ribociclib hydrochloride?

The CAS Registry Number of Ribociclib hydrochloride is 1211443-80-9. It is also known as Ribociclib HCl, LEE011 hydrochloride, LEE011 (hydrochloride).

What is the molecular formula and molecular weight of Ribociclib hydrochloride?

Ribociclib hydrochloride has the molecular formula C23H31ClN8O and a molecular weight of 471 g/mol.

What is Ribociclib hydrochloride used for?

Ribociclib hydrochloride is supplied as a characterised reference material related to Ribociclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ribociclib hydrochloride can I order?

We supply Ribociclib hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ribociclib hydrochloride?

Yes. Every lot of Ribociclib hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ribociclib hydrochloride be shipped internationally?

Yes. We export Ribociclib hydrochloride worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.