Ribociclib-d8

Name: Ribociclib-d8
Brand: Vaqora Chemicals
SKU: VQ-033531

About Ribociclib-d8

Vaqora Chemicals supplies Ribociclib-d8, a stable isotope labelled analogue related to Ribociclib registered under CAS number 2167898-24-8. With the molecular formula C23H30N8O, it has a molar mass of 442.6 g/mol. Alternative names: TMID-1108.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Ribociclib-d8 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Ribociclib

View every impurity, metabolite and intermediate we list for Ribociclib.

Ribociclib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ribociclib-d8
Catalogue No.	VQ-033531
CAS Number	2167898-24-8
IUPAC name	7-cyclopentyl-N,N-dimethyl-2-[[5-(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)-2-pyridinyl]amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide
Molecular formula	C₂₃H₃₀N₈O
Molecular weight	442.6 g/mol
Exact mass	442.3045
Grade	Reference Standard
HSN code	38229090
InChIKey	RHXHGRAEPCAFML-PMCMNDOISA-N
SMILES	[2H]C1(C(N(C(C(N1)([2H])[2H])([2H])[2H])C2=CN=C(C=C2)NC3=NC=C4C=C(N(C4=N3)C5CCCC5)C(=O)N(C)C)([2H])[2H])[2H]
PubChem CID	155808515

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	2 / 7
TPSA	91.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ribociclib-d8?

The CAS Registry Number of Ribociclib-d8 is 2167898-24-8. It is also known as TMID-1108.

What is the molecular formula and molecular weight of Ribociclib-d8?

Ribociclib-d8 has the molecular formula C23H30N8O and a molecular weight of 442.6 g/mol. Its IUPAC name is 7-cyclopentyl-N,N-dimethyl-2-[[5-(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)-2-pyridinyl]amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide.

What is Ribociclib-d8 used for?

Ribociclib-d8 is supplied as a characterised reference material related to Ribociclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ribociclib-d8 can I order?

We supply Ribociclib-d8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ribociclib-d8?

Yes. Every lot of Ribociclib-d8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ribociclib-d8 be shipped internationally?

Yes. We export Ribociclib-d8 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.