Rilpivirine Hydrochloride

Name: Rilpivirine Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-007716

About Rilpivirine Hydrochloride

Vaqora Chemicals supplies Rilpivirine Hydrochloride, a high-purity reference standard of Rilpivirine registered under CAS number 700361-47-3. With the molecular formula C22H19ClN6, it has a molar mass of 402.9 g/mol. Its systematic (IUPAC) name is 4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-dimethylanilino]pyrimidin-2-yl]amino]benzonitrile. Hydrochloride. Alternative names: Edurant and TMC 278 hydrochloride.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Rilpivirine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Rilpivirine Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Rilpivirine

View every impurity, metabolite and intermediate we list for Rilpivirine.

Rilpivirine impurities

Specifications & identifiers

Chemical identifiers
Product name	Rilpivirine Hydrochloride
Catalogue No.	VQ-007716
CAS Number	700361-47-3
Other CAS	500287-72-9
IUPAC name	4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-dimethylanilino]pyrimidin-2-yl]amino]benzonitrile;hydrochloride
Molecular formula	C₂₂H₁₉ClN₆
Molecular weight	402.9 g/mol
Exact mass	402.136
Grade	Reference Standard
HSN code	38229090
InChIKey	KZVVGZKAVZUACK-BJILWQEISA-N
SMILES	CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N.Cl
PubChem CID	11711114

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 6
TPSA	97.4 Å²
Synonyms	Edurant, TMC 278 hydrochloride, R 278474 Hydrochloride, Rilpivirine HCl, TMC278 hydrochloride, Rilpivirine (as hydrochloride), Rilpivirine (hydrochloride), Edurant (TN), rilpivirine monohydrochloride, TMC-278-LA, TMC-278 hydrochloride, Rilpivirine hydrochloride (JAN/USAN)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P305 + P351 + P338, P330, P337 + P317, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rilpivirine Hydrochloride?

The CAS Registry Number of Rilpivirine Hydrochloride is 700361-47-3. It is also known as Edurant, TMC 278 hydrochloride, R 278474 Hydrochloride.

What is the molecular formula and molecular weight of Rilpivirine Hydrochloride?

Rilpivirine Hydrochloride has the molecular formula C22H19ClN6 and a molecular weight of 402.9 g/mol.

What is Rilpivirine Hydrochloride used for?

Rilpivirine Hydrochloride is supplied as a characterised reference material related to Rilpivirine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rilpivirine Hydrochloride can I order?

We supply Rilpivirine Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rilpivirine Hydrochloride?

Yes. Every lot of Rilpivirine Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rilpivirine Hydrochloride be shipped internationally?

Yes. Rilpivirine Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.