Rilpivirine Z-Isomer

Name: Rilpivirine Z-Isomer
Brand: Vaqora Chemicals
SKU: VQ-005772

About Rilpivirine Z-Isomer

Listed under CAS 500287-94-5, Rilpivirine Z-Isomer is an impurity of Rilpivirine available from Vaqora Chemicals at a purity of 96.69%. With the molecular formula C22H18N6, it has a molar mass of 366.4 g/mol. Its systematic (IUPAC) name is 4-[[4-[4-[(Z)-2-cyanoethenyl]-2,6-dimethylanilino]pyrimidin-2-yl]amino]benzonitrile. Alternative names: (Z)-Rilpivirine and (1Z)-Rilpivirine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Rilpivirine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Rilpivirine Z-Isomer in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Rilpivirine

View every impurity, metabolite and intermediate we list for Rilpivirine.

Rilpivirine impurities

Specifications & identifiers

Chemical identifiers
Product name	Rilpivirine Z-Isomer
Catalogue No.	VQ-005772
CAS Number	500287-94-5
IUPAC name	4-[[4-[4-[(Z)-2-cyanoethenyl]-2,6-dimethylanilino]pyrimidin-2-yl]amino]benzonitrile
Molecular formula	C₂₂H₁₈N₆
Molecular weight	366.4 g/mol
Exact mass	366.1593
Grade	Reference Standard
Purity / assay	96.69%
HSN code	38229090
InChIKey	YIBOMRUWOWDFLG-ARJAWSKDSA-N
SMILES	CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C\C#N
PubChem CID	5270790

Physical properties
Physical form	Solid
LogP (XLogP3)	4.5
H-bond donors / acceptors	2 / 6
TPSA	97.4 Å²
Synonyms	(Z)-Rilpivirine, (1Z)-Rilpivirine, (Z)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile, Rilpivirine, (Z)-, Rilpivirine cis isomer, Rilpivirine cis-isomer, Rilpivirine metabolite 43, Rilpivirine Z-Isomer HCl, Rilpivirine (Z-Isomer), 4-[[4-[4-[(Z)-2-cyanovinyl]-2,6-dimethyl-anilino]pyrimidin-2-yl]amino]benzonitrile, 4-{4-[4-((Z)-2-Cyano-vinyl)-2,6-dimethyl-phenylamino]-pyrimidin-2-ylamino}-benzonitrile

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rilpivirine Z-Isomer?

The CAS Registry Number of Rilpivirine Z-Isomer is 500287-94-5. It is also known as (Z)-Rilpivirine, (1Z)-Rilpivirine, (Z)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile.

What is the molecular formula and molecular weight of Rilpivirine Z-Isomer?

Rilpivirine Z-Isomer has the molecular formula C22H18N6 and a molecular weight of 366.4 g/mol. Its IUPAC name is 4-[[4-[4-[(Z)-2-cyanoethenyl]-2,6-dimethylanilino]pyrimidin-2-yl]amino]benzonitrile.

What is Rilpivirine Z-Isomer used for?

Rilpivirine Z-Isomer is supplied as a characterised reference material related to Rilpivirine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rilpivirine Z-Isomer can I order?

We supply Rilpivirine Z-Isomer in Reference Standard (96.69%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rilpivirine Z-Isomer?

Yes. Every lot of Rilpivirine Z-Isomer is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rilpivirine Z-Isomer be shipped internationally?

Yes. We export Rilpivirine Z-Isomer worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.