Riociguat D3

Name: Riociguat D3
Brand: Vaqora Chemicals
SKU: VQ-041924

About Riociguat D3

Vaqora Chemicals supplies Riociguat D3, a stable isotope labelled analogue related to Riociguat registered under CAS number 1304478-72-5. With the molecular formula C20H19FN8O2, it has a molar mass of 422.4 g/mol. It is also known as Riociguat (BAY 63-2521) or EX-A2023.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Riociguat D3 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Riociguat

View every impurity, metabolite and intermediate we list for Riociguat.

Riociguat impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Riociguat D3
Catalogue No.	VQ-041924
CAS Number	1304478-72-5
IUPAC name	methyl N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]pyrimidin-5-yl]-N-methylcarbamate
Molecular formula	C₂₀H₁₉FN₈O₂
Molecular weight	422.4 g/mol
Exact mass	422.1615
Grade	Reference Standard
HSN code	38229090
InChIKey	WXXSNCNJFUAIDG-UHFFFAOYSA-N
SMILES	CN(C1=C(N=C(N=C1N)C2=NN(C3=C2C=CC=N3)CC4=CC=CC=C4F)N)C(=O)OC
PubChem CID	11304743

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	2 / 9
TPSA	138 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Riociguat D3?

The CAS Registry Number of Riociguat D3 is 1304478-72-5. It is also known as Riociguat (BAY 63-2521), EX-A2023, Riocguat-d3.

What is the molecular formula and molecular weight of Riociguat D3?

Riociguat D3 has the molecular formula C20H19FN8O2 and a molecular weight of 422.4 g/mol. Its IUPAC name is methyl N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]pyrimidin-5-yl]-N-methylcarbamate.

What is Riociguat D3 used for?

Riociguat D3 is supplied as a characterised reference material related to Riociguat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Riociguat D3 can I order?

We supply Riociguat D3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Riociguat D3?

Yes. Every lot of Riociguat D3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Riociguat D3 be shipped internationally?

Yes. Riociguat D3 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.