Riociguat Triamino Impurity

Name: Riociguat Triamino Impurity
Brand: Vaqora Chemicals
SKU: VQ-033553

About Riociguat Triamino Impurity

Riociguat Triamino Impurity (CAS 428854-24-4) is an impurity of Riociguat offered by Vaqora Chemicals. The compound has the formula C17H15FN8, corresponding to a molecular weight of 350.4 g/mol. Systematically, it is named 2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]pyrimidine-4,5,6-triamine. Common synonyms include N-Desmethyl-N-desmethylcarbamoly Riociguat and riociguat Intermediates.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Riociguat impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Riociguat Triamino Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Riociguat

View every impurity, metabolite and intermediate we list for Riociguat.

Riociguat impurities

Specifications & identifiers

Chemical identifiers
Product name	Riociguat Triamino Impurity
Catalogue No.	VQ-033553
CAS Number	428854-24-4
IUPAC name	2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]pyrimidine-4,5,6-triamine
Molecular formula	C₁₇H₁₅FN₈
Molecular weight	350.4 g/mol
Exact mass	350.1404
Grade	Reference Standard
HSN code	38229090
InChIKey	RCKYXYXLIJBCOE-UHFFFAOYSA-N
SMILES	C1=CC=C(C(=C1)CN2C3=C(C=CC=N3)C(=N2)C4=NC(=C(C(=N4)N)N)N)F
PubChem CID	11393973

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	3 / 8
TPSA	135 Å²
Synonyms	2-[1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5,6-triamine, 2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidine-4,5,6- triamine, 2-(1-((2-Fluorophenyl)methyl)-1H-pyrazolo(3,4-b)pyridin-3-yl)-4,5,6-pyrimidinetriamine, 2-[1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4,5,6-pyrimidinetriamine, 2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidine-4,5,6-triamine, 2-{1-[(2-fluorophenyl)methyl]-1h-pyrazolo[3,4-b]pyridin-3-yl}pyrimidine-4,5,6-triamine, 2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5,6-triamine, N-Desmethyl-N-desmethylcarbamoly Riociguat, 2-(1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-B]pyridin-3-yl)pyrimidine-4,5,6-triamine, 4,5,6-Pyrimidinetriamine, 2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-, riociguat Intermediates, CS-M2182

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Riociguat Triamino Impurity?

The CAS Registry Number of Riociguat Triamino Impurity is 428854-24-4. It is also known as 2-[1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5,6-triamine, 2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidine-4,5,6- triamine, 2-(1-((2-Fluorophenyl)methyl)-1H-pyrazolo(3,4-b)pyridin-3-yl)-4,5,6-pyrimidinetriamine.

What is the molecular formula and molecular weight of Riociguat Triamino Impurity?

Riociguat Triamino Impurity has the molecular formula C17H15FN8 and a molecular weight of 350.4 g/mol. Its IUPAC name is 2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]pyrimidine-4,5,6-triamine.

What is Riociguat Triamino Impurity used for?

Riociguat Triamino Impurity is supplied as a characterised reference material related to Riociguat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Riociguat Triamino Impurity can I order?

We supply Riociguat Triamino Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Riociguat Triamino Impurity?

Yes. Every lot of Riociguat Triamino Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Riociguat Triamino Impurity be shipped internationally?

Yes. We export Riociguat Triamino Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.