Riociguat EP Impurity B

Name: Riociguat EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-033558

About Riociguat EP Impurity B

Riociguat EP Impurity B (CAS 3052969-92-0) is a pharmacopeial impurity of Riociguat offered by Vaqora Chemicals. Its molecular formula is C20H20N8O2 and its molecular weight is 404.4 g/mol. Its systematic (IUPAC) name is methyl N-[4,6-diamino-2-(1-benzylpyrazolo[5,4-b]pyridin-3-yl)pyrimidin-5-yl]-N-methylcarbamate. Alternative names: Riociguat - Impurity B and 2-Desfluoro-riociguat.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Riociguat to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Riociguat EP Impurity B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Riociguat

View every impurity, metabolite and intermediate we list for Riociguat.

Riociguat impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Riociguat EP Impurity B
Catalogue No.	VQ-033558
CAS Number	3052969-92-0
IUPAC name	methyl N-[4,6-diamino-2-(1-benzylpyrazolo[5,4-b]pyridin-3-yl)pyrimidin-5-yl]-N-methylcarbamate
Molecular formula	C₂₀H₂₀N₈O₂
Molecular weight	404.4 g/mol
Exact mass	404.1709
Grade	Reference Standard
HSN code	38229090
InChIKey	OQVWZKRLCLVLIG-UHFFFAOYSA-N
SMILES	CN(C1=C(N=C(N=C1N)C2=NN(C3=C2C=CC=N3)CC4=CC=CC=C4)N)C(=O)OC
PubChem CID	171382109

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	2 / 8
TPSA	138 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Riociguat EP Impurity B?

The CAS Registry Number of Riociguat EP Impurity B is 3052969-92-0. It is also known as Riociguat - Impurity B, 2-Desfluoro-riociguat, Riociguat Impurity J.

What is the molecular formula and molecular weight of Riociguat EP Impurity B?

Riociguat EP Impurity B has the molecular formula C20H20N8O2 and a molecular weight of 404.4 g/mol. Its IUPAC name is methyl N-[4,6-diamino-2-(1-benzylpyrazolo[5,4-b]pyridin-3-yl)pyrimidin-5-yl]-N-methylcarbamate.

What is Riociguat EP Impurity B used for?

Riociguat EP Impurity B is supplied as a characterised reference material related to Riociguat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Riociguat EP Impurity B can I order?

We supply Riociguat EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Riociguat EP Impurity B?

Yes. Every lot of Riociguat EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Riociguat EP Impurity B be shipped internationally?

Yes. We export Riociguat EP Impurity B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.