Roflumilast N-Oxide-d4

Name: Roflumilast N-Oxide-d4
Brand: Vaqora Chemicals
SKU: VQ-033637

About Roflumilast N-Oxide-d4

Listed under CAS 1794760-31-8, Roflumilast N-Oxide-d4 is a stable isotope labelled analogue related to Roflumilast available from Vaqora Chemicals. Formula C17H14Cl2F2N2O4, molecular weight 423.2 g/mol. Common synonyms include Roflumilast-d4 N-Oxide and TMIH-0502.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Roflumilast N-Oxide-d4 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Roflumilast

View every impurity, metabolite and intermediate we list for Roflumilast.

Roflumilast impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Roflumilast N-Oxide-d4
Catalogue No.	VQ-033637
CAS Number	1794760-31-8
IUPAC name	N-(3,5-dichloro-1-hydroxy-4-pyridinylidene)-4-(difluoromethoxy)-3-[(2,2,3,3-tetradeuteriocyclopropyl)methoxy]benzamide
Molecular formula	C₁₇H₁₄Cl₂F₂N₂O₄
Molecular weight	423.2 g/mol
Exact mass	422.055
Grade	Reference Standard
HSN code	38229090
InChIKey	KHXXMSARUQULRI-LNLMKGTHSA-N
SMILES	[2H]C1(C(C1([2H])[2H])COC2=C(C=CC(=C2)C(=O)N=C3C(=CN(C=C3Cl)O)Cl)OC(F)F)[2H]
PubChem CID	71752097

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	1 / 7
TPSA	71.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Roflumilast N-Oxide-d4?

The CAS Registry Number of Roflumilast N-Oxide-d4 is 1794760-31-8. It is also known as Roflumilast-d4 N-Oxide, TMIH-0502.

What is the molecular formula and molecular weight of Roflumilast N-Oxide-d4?

Roflumilast N-Oxide-d4 has the molecular formula C17H14Cl2F2N2O4 and a molecular weight of 423.2 g/mol. Its IUPAC name is N-(3,5-dichloro-1-hydroxy-4-pyridinylidene)-4-(difluoromethoxy)-3-[(2,2,3,3-tetradeuteriocyclopropyl)methoxy]benzamide.

What is Roflumilast N-Oxide-d4 used for?

Roflumilast N-Oxide-d4 is supplied as a characterised reference material related to Roflumilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Roflumilast N-Oxide-d4 can I order?

We supply Roflumilast N-Oxide-d4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Roflumilast N-Oxide-d4?

Yes. Every lot of Roflumilast N-Oxide-d4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Roflumilast N-Oxide-d4 be shipped internationally?

Yes. We export Roflumilast N-Oxide-d4 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.