Rolapitant Hydrochloride Hydrate

Name: Rolapitant Hydrochloride Hydrate
Brand: Vaqora Chemicals
SKU: VQ-041989

About Rolapitant Hydrochloride Hydrate

Rolapitant Hydrochloride Hydrate (CAS 914462-92-3) is a high-purity reference standard of Rolapitant offered by Vaqora Chemicals. Formula C25H29ClF6N2O3, molecular weight 555.0 g/mol. Alternative names: Rolapitant and Rolapitant hydrochloride.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this Rolapitant standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Rolapitant Hydrochloride Hydrate is dispatched with a Certificate of Analysis (COA) to destinations worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Rolapitant

View every impurity, metabolite and intermediate we list for Rolapitant.

Rolapitant impurities

Specifications & identifiers

Chemical identifiers
Product name	Rolapitant Hydrochloride Hydrate
Catalogue No.	VQ-041989
CAS Number	914462-92-3
IUPAC name	(5S,8S)-8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-1,9-diazaspiro[4.5]decan-2-one;hydrate;hydrochloride
Molecular formula	C₂₅H₂₉ClF₆N₂O₃
Molecular weight	555 g/mol
Exact mass	554.1771
Grade	Reference Standard
HSN code	38229090
InChIKey	GZQWMYVDLCUBQX-WVZIYJGPSA-N
SMILES	C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC[C@]2(CC[C@]3(CCC(=O)N3)CN2)C4=CC=CC=C4.O.Cl
PubChem CID	16203739

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 10
TPSA	51.4 Å²
Synonyms	Rolapitant, Rolapitant hydrochloride, Rolapitant HCl, rolapitant hydrochloride monohydrate, Rolapitant hcl h20, rolapitant.HCl.H2O, rolapitant monohydrochloride monohydrate, rolapitant monohydrochloride, rolapitant hydrochloride (anhydrous), Rolapitant Hydrochloride Anhydrous, Rolapitant HCl hydrate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rolapitant Hydrochloride Hydrate?

The CAS Registry Number of Rolapitant Hydrochloride Hydrate is 914462-92-3. It is also known as Rolapitant, Rolapitant hydrochloride, Rolapitant HCl.

What is the molecular formula and molecular weight of Rolapitant Hydrochloride Hydrate?

Rolapitant Hydrochloride Hydrate has the molecular formula C25H29ClF6N2O3 and a molecular weight of 555 g/mol.

What is Rolapitant Hydrochloride Hydrate used for?

Rolapitant Hydrochloride Hydrate is supplied as a characterised reference material related to Rolapitant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rolapitant Hydrochloride Hydrate can I order?

We supply Rolapitant Hydrochloride Hydrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rolapitant Hydrochloride Hydrate?

Yes. Every lot of Rolapitant Hydrochloride Hydrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rolapitant Hydrochloride Hydrate be shipped internationally?

Yes. We export Rolapitant Hydrochloride Hydrate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.