Ruxolitinib d8

Name: Ruxolitinib d8
Brand: Vaqora Chemicals
SKU: VQ-045063

About Ruxolitinib d8

Ruxolitinib d8 is a stable isotope labelled analogue related to Ruxolitinib carrying the CAS registry number 1513883-39-0. The compound has the formula C17H18N6, corresponding to a molecular weight of 314.41 g/mol. It is also known as Deuruxolitinib or D8-ruxolitinib.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Ruxolitinib d8 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Ruxolitinib

View every impurity, metabolite and intermediate we list for Ruxolitinib.

Ruxolitinib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ruxolitinib d8
Catalogue No.	VQ-045063
CAS Number	1513883-39-0
IUPAC name	(3R)-3-(2,2,3,3,4,4,5,5-octadeuteriocyclopentyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile
Molecular formula	C₁₇H₁₈N₆
Molecular weight	314.41 g/mol
Exact mass	314.2095
Grade	Reference Standard
HSN code	38229090
InChIKey	HFNKQEVNSGCOJV-FBXGHSCESA-N
SMILES	[2H]C1(C(C(C(C1([2H])[2H])([2H])[2H])([2H])[2H])[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3)[2H]
PubChem CID	72704611

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	1 / 4
TPSA	83.2 Å²
Synonyms	Deuruxolitinib, D8-ruxolitinib, CTP-543, Deuruxolitinib (USAN), Deuterated Ruxolitinib

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ruxolitinib d8?

The CAS Registry Number of Ruxolitinib d8 is 1513883-39-0. It is also known as Deuruxolitinib, D8-ruxolitinib, CTP-543.

What is the molecular formula and molecular weight of Ruxolitinib d8?

Ruxolitinib d8 has the molecular formula C17H18N6 and a molecular weight of 314.41 g/mol. Its IUPAC name is (3R)-3-(2,2,3,3,4,4,5,5-octadeuteriocyclopentyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile.

What is Ruxolitinib d8 used for?

Ruxolitinib d8 is supplied as a characterised reference material related to Ruxolitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ruxolitinib d8 can I order?

We supply Ruxolitinib d8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ruxolitinib d8?

Yes. Every lot of Ruxolitinib d8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ruxolitinib d8 be shipped internationally?

Yes. We export Ruxolitinib d8 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.