(S)-Duloxetine Succinamide

Name: (S)-Duloxetine Succinamide
Brand: Vaqora Chemicals
SKU: VQ-012803

About (S)-Duloxetine Succinamide

(S)-Duloxetine Succinamide is a process intermediate or related compound of Duloxetine carrying the CAS registry number 199191-66-7, specified at 98% purity. Formula C22H23NO4S, molecular weight 397.5 g/mol. The IUPAC name is 4-[methyl-[(3S)-3-naphthalen-1-yloxy-3-thiophen-2-ylpropyl]amino]-4-oxobutanoic acid. It is also known as Duloxetine succinamide or Duloxetine USP RC H.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Duloxetine, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Duloxetine

View every impurity, metabolite and intermediate we list for Duloxetine.

Duloxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-Duloxetine Succinamide
Catalogue No.	VQ-012803
CAS Number	199191-66-7
IUPAC name	4-[methyl-[(3S)-3-naphthalen-1-yloxy-3-thiophen-2-ylpropyl]amino]-4-oxobutanoic acid
Molecular formula	C₂₂H₂₃NO₄S
Molecular weight	397.5 g/mol
Exact mass	397.1348
Grade	Reference Standard
Purity / assay	98%
HSN code	2933
InChIKey	AJLVEKJDKWHFDD-IBGZPJMESA-N
SMILES	CN(CC[C@@H](C1=CC=CS1)OC2=CC=CC3=CC=CC=C32)C(=O)CCC(=O)O
PubChem CID	86278283

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	1 / 5
TPSA	95.1 Å²
Synonyms	(S)-4-(Methyl[3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl]amino)-4-oxobutanoic Acid, 4-[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]amino]-4-oxobutanoic acid, Duloxetine succinamide, Butanoic acid, 4-(methyl((3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl)amino)-4-oxo-, (S)-4-(methyl(3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl)amino)-4-oxobutanoic acid, Duloxetine USP RC H, Duloxetine succinamide barium salt, 4-[methyl-[(3S)-3-(1-naphthyloxy)-3-(2-thienyl)propyl]amino]-4-oxo-butanoic acid

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H336May cause drowsiness or dizziness
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P263, P264, P270, P271, P280, P304 + P340, P318, P319, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-Duloxetine Succinamide?

The CAS Registry Number of (S)-Duloxetine Succinamide is 199191-66-7. It is also known as (S)-4-(Methyl[3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl]amino)-4-oxobutanoic Acid, 4-[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]amino]-4-oxobutanoic acid, Duloxetine succinamide.

What is the molecular formula and molecular weight of (S)-Duloxetine Succinamide?

(S)-Duloxetine Succinamide has the molecular formula C22H23NO4S and a molecular weight of 397.5 g/mol. Its IUPAC name is 4-[methyl-[(3S)-3-naphthalen-1-yloxy-3-thiophen-2-ylpropyl]amino]-4-oxobutanoic acid.

What is (S)-Duloxetine Succinamide used for?

(S)-Duloxetine Succinamide is supplied as a characterised reference material related to Duloxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-Duloxetine Succinamide can I order?

We supply (S)-Duloxetine Succinamide in Reference Standard (98%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-Duloxetine Succinamide?

Yes. Every lot of (S)-Duloxetine Succinamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-Duloxetine Succinamide be shipped internationally?

Yes. (S)-Duloxetine Succinamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.