Sacubitril (3R,5S)-Pyrrolidinone Impurity

Name: Sacubitril (3R,5S)-Pyrrolidinone Impurity
Brand: Vaqora Chemicals
SKU: VQ-023706

About Sacubitril (3R,5S)-Pyrrolidinone Impurity

Listed under CAS 1038924-70-7, Sacubitril (3R,5S)-Pyrrolidinone Impurity is an impurity of Sacubitril available from Vaqora Chemicals. With the molecular formula C18H19NO, it has a molar mass of 265.3 g/mol. Its systematic (IUPAC) name is (3R,5S)-3-methyl-5-[(4-phenylphenyl)methyl]pyrrolidin-2-one. It is also known as Cyclic Impurity Of Sacubitril or Sacubitril Impurity A.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Sacubitril impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Sacubitril (3R,5S)-Pyrrolidinone Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	Sacubitril (3R,5S)-Pyrrolidinone Impurity
Catalogue No.	VQ-023706
CAS Number	1038924-70-7
IUPAC name	(3R,5S)-3-methyl-5-[(4-phenylphenyl)methyl]pyrrolidin-2-one
Molecular formula	C₁₈H₁₉NO
Molecular weight	265.3 g/mol
Exact mass	265.1467
Grade	Reference Standard
HSN code	38229090
InChIKey	AFMGAVDATRJOJG-DYVFJYSZSA-N
SMILES	C[C@@H]1C[C@H](NC1=O)CC2=CC=C(C=C2)C3=CC=CC=C3
PubChem CID	66739158

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	1 / 1
TPSA	29.1 Å²
Synonyms	Cyclic Impurity Of Sacubitril, 5-((1,1'-Biphenyl)-4-ylmethyl)-3-methyl-2-pyrrolidinone, (3R,5S)-, 5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-2-pyrrolidinone, (3R,5S)-, (3R,5S)-5-[(Biphenyl-4-yl)methyl]-3-methylpyrrolidin-2-one, (3R,5S)-5-([1,1'-biphenyl]-4-ylmethyl)-3-methylpyrrolidin-2-one, (3R,5S)-5-biphenyl-4-ylmethyl-3-methylpyrrolidin-2-one, Sacubitril Impurity A, trans-5-([1,1'-Biphenyl]-4-ylmethyl)-3-methylpyrrolidin-2-one, (3R,5S)-rel-5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-2-pyrrolidinone (Racemic Mixture), Sacubitril impurity 1

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sacubitril (3R,5S)-Pyrrolidinone Impurity?

The CAS Registry Number of Sacubitril (3R,5S)-Pyrrolidinone Impurity is 1038924-70-7. It is also known as Cyclic Impurity Of Sacubitril, 5-((1,1'-Biphenyl)-4-ylmethyl)-3-methyl-2-pyrrolidinone, (3R,5S)-, 5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-2-pyrrolidinone, (3R,5S)-.

What is the molecular formula and molecular weight of Sacubitril (3R,5S)-Pyrrolidinone Impurity?

Sacubitril (3R,5S)-Pyrrolidinone Impurity has the molecular formula C18H19NO and a molecular weight of 265.3 g/mol. Its IUPAC name is (3R,5S)-3-methyl-5-[(4-phenylphenyl)methyl]pyrrolidin-2-one.

What is Sacubitril (3R,5S)-Pyrrolidinone Impurity used for?

Sacubitril (3R,5S)-Pyrrolidinone Impurity is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sacubitril (3R,5S)-Pyrrolidinone Impurity can I order?

We supply Sacubitril (3R,5S)-Pyrrolidinone Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sacubitril (3R,5S)-Pyrrolidinone Impurity?

Yes. Every lot of Sacubitril (3R,5S)-Pyrrolidinone Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sacubitril (3R,5S)-Pyrrolidinone Impurity be shipped internationally?

Yes. We export Sacubitril (3R,5S)-Pyrrolidinone Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.