Sacubitril Impurity A

Name: Sacubitril Impurity A
Brand: Vaqora Chemicals
SKU: VQ-005861

About Sacubitril Impurity A

Listed under CAS 1039307-95-3, Sacubitril Impurity A is an impurity of Sacubitril available from Vaqora Chemicals, specified at 99% purity. The compound has the formula C18H21NO2, corresponding to a molecular weight of 283.4 g/mol. Its systematic (IUPAC) name is (2R,4S)-4-amino-2-methyl-5-(4-phenylphenyl)pentanoic acid. Common synonyms include Sacubitril Impurity 11 and Valsartan Impurity 17.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Sacubitril, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Sacubitril Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	Sacubitril Impurity A
Catalogue No.	VQ-005861
CAS Number	1039307-95-3
Other CAS	1038924-71-8
IUPAC name	(2R,4S)-4-amino-2-methyl-5-(4-phenylphenyl)pentanoic acid
Molecular formula	C₁₈H₂₁NO₂
Molecular weight	283.4 g/mol
Exact mass	283.1572
Grade	Reference Standard
Purity / assay	99%
HSN code	38229090
InChIKey	WQQLDAFJPWYZCC-DYVFJYSZSA-N
SMILES	C[C@H](C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)N)C(=O)O
PubChem CID	25017085

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	2 / 3
TPSA	63.3 Å²
Synonyms	Sacubitril Impurity 11, (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpentanoic acid, (αR,γS)-γ-Amino-α-methyl[1,1′-biphenyl]-4-pentanoic acid, (2R,4S)-5-([1,1′-Biphenyl]-4-yl)-4-amino-2-methylpentanoic acid, (2R,4S)-4-amino-5-{[1,1'-biphenyl]-4-yl}-2-methylpentanoic acid, Valsartan Impurity 17, (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methyl pentanoic acid, (alphaR,gammaS)-gamma-Amino-alpha-methyl[1,1'-biphenyl]-4-pentanoic acid, 5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpentanoic acid, (2R,4S)-, [1,1'-Biphenyl]-4-pentanoic acid, gamma-amino-alpha-methyl-, (alphaR,gammaS)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sacubitril Impurity A?

The CAS Registry Number of Sacubitril Impurity A is 1039307-95-3. It is also known as Sacubitril Impurity 11, (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpentanoic acid, (αR,γS)-γ-Amino-α-methyl[1,1′-biphenyl]-4-pentanoic acid.

What is the molecular formula and molecular weight of Sacubitril Impurity A?

Sacubitril Impurity A has the molecular formula C18H21NO2 and a molecular weight of 283.4 g/mol. Its IUPAC name is (2R,4S)-4-amino-2-methyl-5-(4-phenylphenyl)pentanoic acid.

What is Sacubitril Impurity A used for?

Sacubitril Impurity A is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sacubitril Impurity A can I order?

We supply Sacubitril Impurity A in Reference Standard (99%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sacubitril Impurity A?

Yes. Every lot of Sacubitril Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sacubitril Impurity A be shipped internationally?

Yes. We export Sacubitril Impurity A worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.