Sacubitril Lactam (3R,5R Isomer)

Name: Sacubitril Lactam (3R,5R Isomer)
Brand: Vaqora Chemicals
SKU: VQ-005862

About Sacubitril Lactam (3R,5R Isomer)

Sacubitril Lactam (3R,5R Isomer) is an impurity of Sacubitril carrying the CAS registry number 2101222-42-6. Its molecular formula is C18H19NO and its molecular weight is 265.3 g/mol. The IUPAC name is (3R,5R)-3-methyl-5-[(4-phenylphenyl)methyl]pyrrolidin-2-one.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Sacubitril to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Sacubitril Lactam (3R,5R Isomer) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	Sacubitril Lactam (3R,5R Isomer)
Catalogue No.	VQ-005862
CAS Number	2101222-42-6
IUPAC name	(3R,5R)-3-methyl-5-[(4-phenylphenyl)methyl]pyrrolidin-2-one
Molecular formula	C₁₈H₁₉NO
Molecular weight	265.3 g/mol
Exact mass	265.1467
Grade	Reference Standard
HSN code	38229090
InChIKey	AFMGAVDATRJOJG-CXAGYDPISA-N
SMILES	C[C@@H]1C[C@@H](NC1=O)CC2=CC=C(C=C2)C3=CC=CC=C3
PubChem CID	145710175

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	1 / 1
TPSA	29.1 Å²
Synonyms	(3R,5R)-5-([1.1'-Biphenyl]-4-ylmethyl)-3-methylpyrrolidin-2-one, (3R,5R)-5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-2-pyrrolidinone, rel-(3R,5R)-5-([1,1′-Biphenyl]-4-ylmethyl)-3-methyl-2-pyrrolidinone, Sacubitril Lactam (3R,5R Isomer), cis-5-([1,1'-Biphenyl]-4-ylmethyl)-3-methylpyrrolidin-2-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sacubitril Lactam (3R,5R Isomer)?

The CAS Registry Number of Sacubitril Lactam (3R,5R Isomer) is 2101222-42-6. It is also known as (3R,5R)-5-([1.1'-Biphenyl]-4-ylmethyl)-3-methylpyrrolidin-2-one, (3R,5R)-5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-2-pyrrolidinone, rel-(3R,5R)-5-([1,1′-Biphenyl]-4-ylmethyl)-3-methyl-2-pyrrolidinone.

What is the molecular formula and molecular weight of Sacubitril Lactam (3R,5R Isomer)?

Sacubitril Lactam (3R,5R Isomer) has the molecular formula C18H19NO and a molecular weight of 265.3 g/mol. Its IUPAC name is (3R,5R)-3-methyl-5-[(4-phenylphenyl)methyl]pyrrolidin-2-one.

What is Sacubitril Lactam (3R,5R Isomer) used for?

Sacubitril Lactam (3R,5R Isomer) is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sacubitril Lactam (3R,5R Isomer) can I order?

We supply Sacubitril Lactam (3R,5R Isomer) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sacubitril Lactam (3R,5R Isomer)?

Yes. Every lot of Sacubitril Lactam (3R,5R Isomer) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sacubitril Lactam (3R,5R Isomer) be shipped internationally?

Yes. We export Sacubitril Lactam (3R,5R Isomer) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.