Isoscopine

Name: Isoscopine
Brand: Vaqora Chemicals
SKU: VQ-042562

About Isoscopine

Isoscopine (CAS 498-46-4) is an impurity of Tiotropium offered by Vaqora Chemicals. Formula C8H13NO2, molecular weight 155.19 g/mol. Systematically, it is named (1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol. Alternative names: Scopine and 6,7-Epoxytropine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Tiotropium, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tiotropium

View every impurity, metabolite and intermediate we list for Tiotropium.

Tiotropium impurities

Specifications & identifiers

Chemical identifiers
Product name	Isoscopine
Catalogue No.	VQ-042562
CAS Number	498-46-4
IUPAC name	(1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol
Molecular formula	C₈H₁₃NO₂
Molecular weight	155.19 g/mol
Exact mass	155.0946
Grade	Reference Standard
HSN code	38229090
InChIKey	FIMXSEMBHGTNKT-UPGAHCIJSA-N
SMILES	CN1[C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)O
PubChem CID	1274465

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.2
H-bond donors / acceptors	1 / 3
TPSA	36 Å²
Synonyms	(1R,2R,4S,5S,7r)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol, Scopine, (1R,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol, (1R,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo(3.3.1.02,4)nonan-7-ol, 6,7-Epoxytropine, (1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol, Scopin, rel-(1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol, Scopanol, (1R,2R,4S,5S,7R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0,2,4]nonan-7-ol, (1R,2R,4S,5S,7r)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]nonan-7-ol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Isoscopine?

The CAS Registry Number of Isoscopine is 498-46-4. It is also known as (1R,2R,4S,5S,7r)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol, Scopine, (1R,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol.

What is the molecular formula and molecular weight of Isoscopine?

Isoscopine has the molecular formula C8H13NO2 and a molecular weight of 155.19 g/mol. Its IUPAC name is (1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol.

What is Isoscopine used for?

Isoscopine is supplied as a characterised reference material related to Tiotropium. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Isoscopine can I order?

We supply Isoscopine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Isoscopine?

Yes. Every lot of Isoscopine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Isoscopine be shipped internationally?

Yes. We export Isoscopine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.