Sitagliptin Hydrochloride

Name: Sitagliptin Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-007757

About Sitagliptin Hydrochloride

Vaqora Chemicals supplies Sitagliptin Hydrochloride, a high-purity reference standard of Sitagliptin registered under CAS number 486459-71-6. Formula C16H16ClF6N5O, molecular weight 443.77 g/mol. Alternative names: Sitagliptin monohydrochloride and Sitagliptin HCl.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Sitagliptin standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Sitagliptin Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Sitagliptin Hydrochloride
Catalogue No.	VQ-007757
CAS Number	486459-71-6
Other CAS	654671-78-0, 486460-32-6, 862156-92-1
IUPAC name	(3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride
Molecular formula	C₁₆H₁₆ClF₆N₅O
Molecular weight	443.77 g/mol
Exact mass	443.0948
Grade	Reference Standard
HSN code	38229090
InChIKey	PNXSHNOORJKXDW-SBSPUUFOSA-N
SMILES	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.Cl
PubChem CID	11476287

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 10
TPSA	77 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sitagliptin Hydrochloride?

The CAS Registry Number of Sitagliptin Hydrochloride is 486459-71-6. It is also known as Sitagliptin monohydrochloride, Sitagliptin HCl.

What is the molecular formula and molecular weight of Sitagliptin Hydrochloride?

Sitagliptin Hydrochloride has the molecular formula C16H16ClF6N5O and a molecular weight of 443.77 g/mol.

What is Sitagliptin Hydrochloride used for?

Sitagliptin Hydrochloride is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sitagliptin Hydrochloride can I order?

We supply Sitagliptin Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sitagliptin Hydrochloride?

Yes. Every lot of Sitagliptin Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sitagliptin Hydrochloride be shipped internationally?

Yes. Sitagliptin Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.