Sitagliptin EP Impurity C (Freebase)

Name: Sitagliptin EP Impurity C (Freebase)
Brand: Vaqora Chemicals
SKU: VQ-006694

About Sitagliptin EP Impurity C (Freebase)

Sitagliptin EP Impurity C (Freebase) (CAS 945261-48-3) is a pharmacopeial impurity of Sitagliptin offered by Vaqora Chemicals. With the molecular formula C16H16F5N5O, it has a molar mass of 389.32 g/mol. It is also known as Sitagliptin EP Impurity C or Sitagliptin 2,4-Difluoro Analogue.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Sitagliptin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Sitagliptin EP Impurity C (Freebase) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Sitagliptin EP Impurity C (Freebase)
Catalogue No.	VQ-006694
CAS Number	945261-48-3
Other CAS	1345822-86-7
IUPAC name	(3R)-3-amino-4-(2,4-difluorophenyl)-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]butan-1-one
Molecular formula	C₁₆H₁₆F₅N₅O
Molecular weight	389.32 g/mol
Exact mass	389.1275
Grade	Reference Standard
HSN code	38229090
InChIKey	FWMYEIUDYSGXQO-LLVKDONJSA-N
SMILES	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=C(C=C(C=C3)F)F)N
PubChem CID	11957945

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	1 / 9
TPSA	77 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sitagliptin EP Impurity C (Freebase)?

The CAS Registry Number of Sitagliptin EP Impurity C (Freebase) is 945261-48-3. It is also known as Sitagliptin EP Impurity C, Sitagliptin 2,4-Difluoro Analogue.

What is the molecular formula and molecular weight of Sitagliptin EP Impurity C (Freebase)?

Sitagliptin EP Impurity C (Freebase) has the molecular formula C16H16F5N5O and a molecular weight of 389.32 g/mol. Its IUPAC name is (3R)-3-amino-4-(2,4-difluorophenyl)-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]butan-1-one.

What is Sitagliptin EP Impurity C (Freebase) used for?

Sitagliptin EP Impurity C (Freebase) is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sitagliptin EP Impurity C (Freebase) can I order?

We supply Sitagliptin EP Impurity C (Freebase) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sitagliptin EP Impurity C (Freebase)?

Yes. Every lot of Sitagliptin EP Impurity C (Freebase) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sitagliptin EP Impurity C (Freebase) be shipped internationally?

Yes. We export Sitagliptin EP Impurity C (Freebase) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.