Tadalafil Desmethylene Impurity

Name: Tadalafil Desmethylene Impurity
Brand: Vaqora Chemicals
SKU: VQ-028185

About Tadalafil Desmethylene Impurity

Tadalafil Desmethylene Impurity is a metabolite or degradation product of Tadalafil carrying the CAS registry number 171489-03-5. Its molecular formula is C21H19N3O4 and its molecular weight is 377.4 g/mol. Alternative names: Desmethylene Tadalafil and Tadalafil catechol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Tadalafil, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Tadalafil Desmethylene Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Tadalafil

View every impurity, metabolite and intermediate we list for Tadalafil.

Tadalafil impurities

Specifications & identifiers

Chemical identifiers
Product name	Tadalafil Desmethylene Impurity
Catalogue No.	VQ-028185
CAS Number	171489-03-5
IUPAC name	(2R,8R)-2-(3,4-dihydroxyphenyl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione
Molecular formula	C₂₁H₁₉N₃O₄
Molecular weight	377.4 g/mol
Exact mass	377.1376
Grade	Reference Standard
HSN code	38229090
InChIKey	HZSPPSAESSMSNY-FOIQADDNSA-N
SMILES	CN1CC(=O)N2[C@@H](C1=O)CC3=C([C@H]2C4=CC(=C(C=C4)O)O)NC5=CC=CC=C35
PubChem CID	9864503

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	3 / 4
TPSA	96.9 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tadalafil Desmethylene Impurity?

The CAS Registry Number of Tadalafil Desmethylene Impurity is 171489-03-5. It is also known as Desmethylene Tadalafil, Tadalafil catechol, Tadalafil IMpurity: IMpurity I.

What is the molecular formula and molecular weight of Tadalafil Desmethylene Impurity?

Tadalafil Desmethylene Impurity has the molecular formula C21H19N3O4 and a molecular weight of 377.4 g/mol. Its IUPAC name is (2R,8R)-2-(3,4-dihydroxyphenyl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione.

What is Tadalafil Desmethylene Impurity used for?

Tadalafil Desmethylene Impurity is supplied as a characterised reference material related to Tadalafil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tadalafil Desmethylene Impurity can I order?

We supply Tadalafil Desmethylene Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tadalafil Desmethylene Impurity?

Yes. Every lot of Tadalafil Desmethylene Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tadalafil Desmethylene Impurity be shipped internationally?

Yes. We export Tadalafil Desmethylene Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.