Thiocolchicoside EP Impurity B

Name: Thiocolchicoside EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-023881

About Thiocolchicoside EP Impurity B

Vaqora Chemicals supplies Thiocolchicoside EP Impurity B, a pharmacopeial impurity of Thiocolchicoside registered under CAS number 2730-71-4. With the molecular formula C22H25NO5S, it has a molar mass of 415.5 g/mol. Systematically, it is named N-[(7S)-1,2,3-trimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide. Common synonyms include Thiocolchicine and Thiocolchicoside Hydrate - Impurity B.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This Thiocolchicoside impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Thiocolchicoside EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Thiocolchicoside

View every impurity, metabolite and intermediate we list for Thiocolchicoside.

Thiocolchicoside impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Thiocolchicoside EP Impurity B
Catalogue No.	VQ-023881
CAS Number	2730-71-4
IUPAC name	N-[(7S)-1,2,3-trimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Molecular formula	C₂₂H₂₅NO₅S
Molecular weight	415.5 g/mol
Exact mass	415.1453
Grade	Reference Standard
HSN code	38229090
InChIKey	CMEGANPVAXDBPL-INIZCTEOSA-N
SMILES	CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)SC)OC)OC)OC
PubChem CID	17648

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	1 / 6
TPSA	99.2 Å²
Synonyms	Thiocolchicine, Thiocolchicoside Hydrate - Impurity B, Thiocholchicine, Colchicine, 10-thio-, Colchicine, 10-demethoxy-10-(methylthio)-, 10-Demethoxy-10-(methylthio)colchicine, N-(1,2,3-trimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide, 10-Thio-colchicine, 10-Demethoxy-10-methylthiocolchicine, 10-Demethoxy-10- (methylthio)colchicine

Safety & hazard information (GHS)

Corrosive

Toxic

Health hazard

Signal word: Danger

Hazard statements

H300+H330Fatal if swallowed or if inhaled
H300Fatal if swallowed
H318Causes serious eye damage
H330Fatal if inhaled
H340May cause genetic defects

Precautionary statements: P203, P260, P264, P264 + P265, P270, P271, P280, P284, P301 + P316, P304 + P340, P305 + P354 + P338, P316, P317, P318, P320, P321, P330, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Thiocolchicoside EP Impurity B?

The CAS Registry Number of Thiocolchicoside EP Impurity B is 2730-71-4. It is also known as Thiocolchicine, Thiocolchicoside Hydrate - Impurity B, Thiocholchicine.

What is the molecular formula and molecular weight of Thiocolchicoside EP Impurity B?

Thiocolchicoside EP Impurity B has the molecular formula C22H25NO5S and a molecular weight of 415.5 g/mol. Its IUPAC name is N-[(7S)-1,2,3-trimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide.

What is Thiocolchicoside EP Impurity B used for?

Thiocolchicoside EP Impurity B is supplied as a characterised reference material related to Thiocolchicoside. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Thiocolchicoside EP Impurity B can I order?

We supply Thiocolchicoside EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Thiocolchicoside EP Impurity B?

Yes. Every lot of Thiocolchicoside EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Thiocolchicoside EP Impurity B be shipped internationally?

Yes. Thiocolchicoside EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.