Thiocolchicoside EP Impurity C

Name: Thiocolchicoside EP Impurity C
Brand: Vaqora Chemicals
SKU: VQ-023879

About Thiocolchicoside EP Impurity C

Listed under CAS 87424-25-7, Thiocolchicoside EP Impurity C is a pharmacopeial impurity of Thiocolchicoside available from Vaqora Chemicals. The compound has the formula C21H23NO5S, corresponding to a molecular weight of 401.5 g/mol. The IUPAC name is N-[(7S)-3-hydroxy-1,2-dimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide. It is also known as 3-O-Demethyl Thiocolchicine or Thiocolchicoside Hydrate - Impurity C.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Thiocolchicoside, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Thiocolchicoside EP Impurity C is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Thiocolchicoside

View every impurity, metabolite and intermediate we list for Thiocolchicoside.

Thiocolchicoside impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Thiocolchicoside EP Impurity C
Catalogue No.	VQ-023879
CAS Number	87424-25-7
IUPAC name	N-[(7S)-3-hydroxy-1,2-dimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Molecular formula	C₂₁H₂₃NO₅S
Molecular weight	401.5 g/mol
Exact mass	401.1297
Grade	Reference Standard
HSN code	38229090
InChIKey	PKYOHQGXPPVIGD-HNNXBMFYSA-N
SMILES	CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)SC)OC)OC)O
PubChem CID	84076

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	2 / 6
TPSA	110 Å²
Synonyms	3-O-Demethyl Thiocolchicine, Thiocolchicoside Hydrate - Impurity C, 3-Demethylthiocolchicine, 3-Desmethylthiocolchicine, 3-Demethyl Thiocolchicine, 3-O-Demethylthiocolchicine, O(sup 3)-Demethyl-10-thiocolchicine, Colchicine, O(sup 3)-demethyl-10-thio-, Thiocolchicoside Impurity 1

Safety & hazard information (GHS)

Corrosive

Toxic

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H318Causes serious eye damage
H330Fatal if inhaled

Precautionary statements: P260, P264, P264 + P265, P270, P271, P280, P284, P301 + P316, P304 + P340, P305 + P354 + P338, P316, P317, P320, P321, P330, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Thiocolchicoside EP Impurity C?

The CAS Registry Number of Thiocolchicoside EP Impurity C is 87424-25-7. It is also known as 3-O-Demethyl Thiocolchicine, Thiocolchicoside Hydrate - Impurity C, 3-Demethylthiocolchicine.

What is the molecular formula and molecular weight of Thiocolchicoside EP Impurity C?

Thiocolchicoside EP Impurity C has the molecular formula C21H23NO5S and a molecular weight of 401.5 g/mol. Its IUPAC name is N-[(7S)-3-hydroxy-1,2-dimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide.

What is Thiocolchicoside EP Impurity C used for?

Thiocolchicoside EP Impurity C is supplied as a characterised reference material related to Thiocolchicoside. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Thiocolchicoside EP Impurity C can I order?

We supply Thiocolchicoside EP Impurity C in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Thiocolchicoside EP Impurity C?

Yes. Every lot of Thiocolchicoside EP Impurity C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Thiocolchicoside EP Impurity C be shipped internationally?

Yes. Thiocolchicoside EP Impurity C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.