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VAQORATofacitinib Amine Impurity
Synonyms: N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine · (3R,4R)-Methyl{(4-methylpiperidin-3-yl)(7H- pyrrolo[2,3-d]pyrimidin-4-yl)}amine · Tofacitinib Impurity M · N-Methyl-N-((3R,4R)-4-methyl-3-piperidinyl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine
CAS No.477600-74-1
FormulaC13H19N5
Mol. weight245.32
Catalogue No.VQ-006041
PurityReference Standard
HSN38229090
Tofacitinib Amine Impurity (CAS 477600-74-1) – Tofacitinib impurity standard. C13H19N5, MW 245.32. Request a quote: COA, bulk packs and worldwide export.
Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
250 mg
Bulk / custom pack · kg to MT
Enquire Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing
About Tofacitinib Amine Impurity
Tofacitinib Amine Impurity is an impurity of Tofacitinib carrying the CAS registry number 477600-74-1. With the molecular formula C13H19N5, it has a molar mass of 245.32 g/mol. Systematically, it is named N-methyl-N-[(3R,4R)-4-methylpiperidin-3-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine. It is also known as Tofacitinib Impurity M.
The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.
As a characterised impurity of Tofacitinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.
Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
Related to Tofacitinib
View every impurity, metabolite and intermediate we list for Tofacitinib.
Tofacitinib impuritiesSpecifications & identifiers
| Product name | Tofacitinib Amine Impurity |
|---|---|
| Catalogue No. | VQ-006041 |
| CAS Number | 477600-74-1 |
| Other CAS | 1260590-51-9 |
| IUPAC name | N-methyl-N-[(3R,4R)-4-methylpiperidin-3-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
| Molecular formula | C13H19N5 |
| Molecular weight | 245.32 g/mol |
| Exact mass | 245.164 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | XRIARWQZLGCQDM-KOLCDFICSA-N |
| SMILES | C[C@@H]1CCNC[C@@H]1N(C)C2=NC=NC3=C2C=CN3 |
| PubChem CID | 23401507 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 1.7 |
| H-bond donors / acceptors | 2 / 4 |
| TPSA | 56.8 Ų |
| Synonyms | N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, (3R,4R)-Methyl{(4-methylpiperidin-3-yl)(7H- pyrrolo[2,3-d]pyrimidin-4-yl)}amine, Tofacitinib Impurity M, N-Methyl-N-((3R,4R)-4-methyl-3-piperidinyl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine, N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, N-methyl-N-[(3R,4R)-4-methyl-3-piperidyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, 1H-Pyrrolo[2,3-d]pyrimidin-4-amine,N-methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-, 7H-Pyrrolo(2,3-d)pyrimidin-4-amine, N-methyl-N-((3R,4R)-4-methyl-3-piperidinyl)-, 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, N-methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-, rel-, N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine, Methyl-((3R,4R)-4-methyl-piperidin-3-yl)-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine, methyl-[(3R,4R)-4-methyl-piperidin-3-yl]-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine |
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Frequently asked questions
What is the CAS number of Tofacitinib Amine Impurity?
The CAS Registry Number of Tofacitinib Amine Impurity is 477600-74-1. It is also known as N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, (3R,4R)-Methyl{(4-methylpiperidin-3-yl)(7H- pyrrolo[2,3-d]pyrimidin-4-yl)}amine, Tofacitinib Impurity M.
What is the molecular formula and molecular weight of Tofacitinib Amine Impurity?
Tofacitinib Amine Impurity has the molecular formula C13H19N5 and a molecular weight of 245.32 g/mol. Its IUPAC name is N-methyl-N-[(3R,4R)-4-methylpiperidin-3-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine.
What is Tofacitinib Amine Impurity used for?
Tofacitinib Amine Impurity is supplied as a characterised reference material related to Tofacitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Tofacitinib Amine Impurity can I order?
We supply Tofacitinib Amine Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Tofacitinib Amine Impurity?
Yes. Every lot of Tofacitinib Amine Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Tofacitinib Amine Impurity be shipped internationally?
Yes. We export Tofacitinib Amine Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
Enquire about Tofacitinib Amine Impurity
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