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VAQORATofacitinib Impurity 24
Synonyms: 4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-1H-Pyrrolo[2,3-d]pyrimidine · 4′-Chloro-4,7′-bi-7H-pyrrolo[2,3-d]pyrimidine · [4-Chloro-7-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-7H-pyrrolo[2,3-d]pyrimidine] · 4'-Chloro-7H-4,7'-bipyrrolo[2,3-d]pyrimidine
CAS No.134965-85-8
FormulaC12H7ClN6
Mol. weight270.68
Catalogue No.VQ-006044
PurityReference Standard
HSN38229090
Tofacitinib Impurity 24 (CAS 134965-85-8) – Tofacitinib impurity standard. C12H7ClN6, MW 270.68. Buy from Vaqora Chemicals with COA and worldwide shipping.
Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing
About Tofacitinib Impurity 24
Tofacitinib Impurity 24 is an impurity of Tofacitinib carrying the CAS registry number 134965-85-8. Its molecular formula is C12H7ClN6 and its molecular weight is 270.68 g/mol. Its systematic (IUPAC) name is 4-chloro-7-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolo[2,3-d]pyrimidine. It is also known as 4′-Chloro-4,7′-bi-7H-pyrrolo[2,3-d]pyrimidine or 4'-Chloro-7H-4,7'-bipyrrolo[2,3-d]pyrimidine.
The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.
Pharmaceutical QC and development laboratories use this impurity standard of Tofacitinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
We offer Tofacitinib Impurity 24 in 10 mg, 25 mg and 50 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
Related to Tofacitinib
View every impurity, metabolite and intermediate we list for Tofacitinib.
Tofacitinib impuritiesSpecifications & identifiers
| Product name | Tofacitinib Impurity 24 |
|---|---|
| Catalogue No. | VQ-006044 |
| CAS Number | 134965-85-8 |
| IUPAC name | 4-chloro-7-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolo[2,3-d]pyrimidine |
| Molecular formula | C12H7ClN6 |
| Molecular weight | 270.68 g/mol |
| Exact mass | 270.0421 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | VKXBNSZBGQFCPE-UHFFFAOYSA-N |
| SMILES | C1=CNC2=C1C(=NC=N2)N3C=CC4=C3N=CN=C4Cl |
| PubChem CID | 15726011 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 2.3 |
| H-bond donors / acceptors | 1 / 4 |
| TPSA | 72.3 Ų |
| Synonyms | 4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-1H-Pyrrolo[2,3-d]pyrimidine, 4′-Chloro-4,7′-bi-7H-pyrrolo[2,3-d]pyrimidine, [4-Chloro-7-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-7H-pyrrolo[2,3-d]pyrimidine], 4'-Chloro-7H-4,7'-bipyrrolo[2,3-d]pyrimidine, 4'-Chloro-4,7'-bi-7H-pyrrolo[2,3-d]pyrimidine, 4'-Chloro-4,7'-bi-7H-pyrrolo(2,3-d)pyrimidine, 4-chloro-7-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-7H-pyrrolo[2,3-d]pyrimidine, 4-Chloro-7-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-7H-pyrrolo[2,3-d]pyrimidine, 4,7'-Bi-7H-pyrrolo[2,3-d]pyrimidine, 4'-chloro-, 1H-Pyrrolo[2,3-d]pyrimidine, 4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)- |
Safety & hazard information (GHS)
Signal word: Warning
Hazard statements
H302Harmful if swallowedH315Causes skin irritationH319Causes serious eye irritationH335May cause respiratory irritation
Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Tofacitinib Impurity 24?
The CAS Registry Number of Tofacitinib Impurity 24 is 134965-85-8. It is also known as 4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-1H-Pyrrolo[2,3-d]pyrimidine, 4′-Chloro-4,7′-bi-7H-pyrrolo[2,3-d]pyrimidine, [4-Chloro-7-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-7H-pyrrolo[2,3-d]pyrimidine].
What is the molecular formula and molecular weight of Tofacitinib Impurity 24?
Tofacitinib Impurity 24 has the molecular formula C12H7ClN6 and a molecular weight of 270.68 g/mol. Its IUPAC name is 4-chloro-7-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolo[2,3-d]pyrimidine.
What is Tofacitinib Impurity 24 used for?
Tofacitinib Impurity 24 is supplied as a characterised reference material related to Tofacitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Tofacitinib Impurity 24 can I order?
We supply Tofacitinib Impurity 24 in Reference Standard grade, in 10 mg, 25 mg, 50 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Tofacitinib Impurity 24?
Yes. Every lot of Tofacitinib Impurity 24 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Tofacitinib Impurity 24 be shipped internationally?
Yes. Tofacitinib Impurity 24 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
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