Trans-4-Hydroxy-L-proline-D3

Name: Trans-4-Hydroxy-L-proline-D3
Brand: Vaqora Chemicals
SKU: VQ-041175

About Trans-4-Hydroxy-L-proline-D3

Vaqora Chemicals supplies Trans-4-Hydroxy-L-proline-D3, a stable isotope labelled analogue related to Proline registered under CAS number 1356016-86-8. Its molecular formula is C5H9NO3 and its molecular weight is 134.15 g/mol. Systematically, it is named (2S,4R)-2,5,5-trideuterio-4-hydroxypyrrolidine-2-carboxylic acid. Alternative names: L-Hydroxyproline-d3 and trans-4-Hydroxy-L-proline-2,5,5-d3.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Proline and related analytes in bioanalytical, pharmacokinetic and impurity studies. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Trans-4-Hydroxy-L-proline-D3 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Proline

View every impurity, metabolite and intermediate we list for Proline.

Proline impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Trans-4-Hydroxy-L-proline-D3
Catalogue No.	VQ-041175
CAS Number	1356016-86-8
IUPAC name	(2S,4R)-2,5,5-trideuterio-4-hydroxypyrrolidine-2-carboxylic acid
Molecular formula	C₅H₉NO₃
Molecular weight	134.15 g/mol
Exact mass	134.0771
Grade	Reference Standard
HSN code	38229090
InChIKey	PMMYEEVYMWASQN-QAFFOARNSA-N
SMILES	[2H][C@]1(C[C@H](C(N1)([2H])[2H])O)C(=O)O
PubChem CID	71749212

Physical properties
Physical form	Solid
LogP (XLogP3)	-3.3
H-bond donors / acceptors	3 / 4
TPSA	69.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Trans-4-Hydroxy-L-proline-D3?

The CAS Registry Number of Trans-4-Hydroxy-L-proline-D3 is 1356016-86-8. It is also known as L-Hydroxyproline-d3, trans-4-Hydroxy-L-proline-2,5,5-d3, Hydroxyproline-2,5,5-d3.

What is the molecular formula and molecular weight of Trans-4-Hydroxy-L-proline-D3?

Trans-4-Hydroxy-L-proline-D3 has the molecular formula C5H9NO3 and a molecular weight of 134.15 g/mol. Its IUPAC name is (2S,4R)-2,5,5-trideuterio-4-hydroxypyrrolidine-2-carboxylic acid.

What is Trans-4-Hydroxy-L-proline-D3 used for?

Trans-4-Hydroxy-L-proline-D3 is supplied as a characterised reference material related to Proline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Trans-4-Hydroxy-L-proline-D3 can I order?

We supply Trans-4-Hydroxy-L-proline-D3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Trans-4-Hydroxy-L-proline-D3?

Yes. Every lot of Trans-4-Hydroxy-L-proline-D3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Trans-4-Hydroxy-L-proline-D3 be shipped internationally?

Yes. We export Trans-4-Hydroxy-L-proline-D3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.