Trimethoprim-d3

Name: Trimethoprim-d3
Brand: Vaqora Chemicals
SKU: VQ-042704

About Trimethoprim-d3

Vaqora Chemicals supplies Trimethoprim-d3, a stable isotope labelled analogue related to Trimethoprim registered under CAS number 1189923-38-3. With the molecular formula C14H18N4O3, it has a molar mass of 293.34 g/mol. Systematically, it is named 5-[[3,5-dimethoxy-4-(trideuteriomethoxy)phenyl]methyl]pyrimidine-2,4-diamine. Common synonyms include Trimethoprim-d3 (Major) and Trimethoprim D3 (4-methoxy D3).

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Trimethoprim-d3 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Trimethoprim

View every impurity, metabolite and intermediate we list for Trimethoprim.

Trimethoprim impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Trimethoprim-d3
Catalogue No.	VQ-042704
CAS Number	1189923-38-3
IUPAC name	5-[[3,5-dimethoxy-4-(trideuteriomethoxy)phenyl]methyl]pyrimidine-2,4-diamine
Molecular formula	C₁₄H₁₈N₄O₃
Molecular weight	293.34 g/mol
Exact mass	293.1567
Grade	Reference Standard
HSN code	38229090
InChIKey	IEDVJHCEMCRBQM-HPRDVNIFSA-N
SMILES	[2H]C([2H])([2H])OC1=C(C=C(C=C1OC)CC2=CN=C(N=C2N)N)OC
PubChem CID	46783191

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	2 / 7
TPSA	106 Å²
Synonyms	Trimethoprim-d3 (Major), Trimethoprim D3 (4-methoxy D3), TMID-0815, 5-(3,5-dimethoxy-4-(methoxy-d3)benzyl)pyrimidine-2,4-diamine, 5-({3,5-Dimethoxy-4-[(~2~H_3_)methyloxy]phenyl}methyl)pyrimidine-2,4-diamine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Trimethoprim-d3?

The CAS Registry Number of Trimethoprim-d3 is 1189923-38-3. It is also known as Trimethoprim-d3 (Major), Trimethoprim D3 (4-methoxy D3), TMID-0815.

What is the molecular formula and molecular weight of Trimethoprim-d3?

Trimethoprim-d3 has the molecular formula C14H18N4O3 and a molecular weight of 293.34 g/mol. Its IUPAC name is 5-[[3,5-dimethoxy-4-(trideuteriomethoxy)phenyl]methyl]pyrimidine-2,4-diamine.

What is Trimethoprim-d3 used for?

Trimethoprim-d3 is supplied as a characterised reference material related to Trimethoprim. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Trimethoprim-d3 can I order?

We supply Trimethoprim-d3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Trimethoprim-d3?

Yes. Every lot of Trimethoprim-d3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Trimethoprim-d3 be shipped internationally?

Yes. We export Trimethoprim-d3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.