Trioctylphosphine oxide, GR 99%+

Name: Trioctylphosphine oxide, GR 99%+
Brand: Vaqora Chemicals
SKU: VQ-018668

About Trioctylphosphine oxide, GR 99%+

Trioctylphosphine oxide (CAS 78-50-2) is a catalyst / ligand offered by Vaqora Chemicals (AR grade) with a typical assay of ≥99%. The compound has the formula C24H51OP, corresponding to a molecular weight of 386.6 g/mol. Its systematic (IUPAC) name is 1-dioctylphosphoryloctane. Common synonyms include TOPO and Tri-n-octylphosphine oxide.

In its supplied form it is white powder or crystals. Literature values give a melting point of 52-57 °C and a boiling point of 201-202 °C. Keep the container tightly sealed and store it in a cool, dry area. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Key uses span cross-coupling reactions, homogeneous catalysis, asymmetric synthesis and coordination chemistry. Our customers for this product work in academic and industrial research, pharmaceutical manufacturing and oil, gas and petrochemicals.

We offer Trioctylphosphine oxide in 10 g, 25 g, 100 g and 1 kg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Cross-coupling reactions
Homogeneous catalysis
Asymmetric synthesis
Coordination chemistry

Industries

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Trioctylphosphine oxide, GR 99%+
Catalogue No.	VQ-018668
CAS Number	78-50-2
IUPAC name	1-dioctylphosphoryloctane
Molecular formula	C₂₄H₅₁OP
Molecular weight	386.6 g/mol
Exact mass	386.3678
Grade	AR
Purity / assay	≥99%
HSN code	29319090
InChIKey	ZMBHCYHQLYEYDV-UHFFFAOYSA-N
SMILES	CCCCCCCCP(=O)(CCCCCCCC)CCCCCCCC
PubChem CID	65577

Physical properties
Physical form	Crystalline
Appearance	White powder or crystals
Melting point	52-57 °C
Boiling point	201-202 °C
LogP (XLogP3)	9.6
H-bond donors / acceptors	0 / 1
TPSA	17.1 Å²
Synonyms	TOPO, Tri-n-octylphosphine oxide, Phosphine oxide, trioctyl-, Cyanex 921, Hostarex PX 324, Trioctyl phosphine oxide, 1-(dioctylphosphoryl)octane, C24H51OP, trioctylphosphino-1-one, tri-n-octylphosphineoxide, (OCT)3PO, Trioctyl(oxo)-lambda~5~-phosphane

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage

Precautionary statements: P261, P264, P264 + P265, P272, P280, P302 + P352, P305 + P354 + P338, P317, P321, P332 + P317, P333 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 78-50-2

Extra Pure

Trioctylphosphine oxide, extra pure >99%

CAS: 78-50-2
Formula: C₂₄H₅₁OP
MW: 386.6 g/mol

VQ-045945

Technical

Trioctylphosphine oxide, technical grade, 90%

CAS: 78-50-2
Formula: C₂₄H₅₁OP
MW: 386.6 g/mol

VQ-011625

Frequently asked questions

What is the CAS number of Trioctylphosphine oxide, GR 99%+?

The CAS Registry Number of Trioctylphosphine oxide, GR 99%+ is 78-50-2. It is also known as TOPO, Tri-n-octylphosphine oxide, Phosphine oxide, trioctyl-.

What is the molecular formula and molecular weight of Trioctylphosphine oxide, GR 99%+?

Trioctylphosphine oxide, GR 99%+ has the molecular formula C24H51OP and a molecular weight of 386.6 g/mol. Its IUPAC name is 1-dioctylphosphoryloctane.

Which grade and pack sizes of Trioctylphosphine oxide, GR 99%+ can I order?

We supply Trioctylphosphine oxide, GR 99%+ in AR (≥99%) grade, in 10 g, 25 g, 100 g, 1 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Trioctylphosphine oxide, GR 99%+?

Yes. Every lot of Trioctylphosphine oxide, GR 99%+ is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Trioctylphosphine oxide, GR 99%+ be shipped internationally?

Yes. Trioctylphosphine oxide, GR 99%+ is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.