Tris hydrochloride, EP, AR

Name: Tris hydrochloride, EP, AR
Brand: Vaqora Chemicals
SKU: VQ-047286

About Tris hydrochloride, EP, AR

Tris hydrochloride is a biological buffer in EP / AR grade carrying the CAS registry number 1185-53-1. With the molecular formula C4H12ClNO3, it has a molar mass of 157.59 g/mol. Common synonyms include Tris(hydroxymethyl)aminomethane hydrochloride and Tromethamine hydrochloride.

Store in a tightly closed container in a cool, dry and well-ventilated place. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

It is commonly used for buffer preparation, cell culture and electrophoresis and chromatography. Buyers come mainly from academic and industrial research and diagnostics and biotechnology.

Standard pack sizes are 100 g, 500 g, 1 kg and 5 kg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Buffer preparation
Cell culture
Electrophoresis & chromatography

Industries

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Tris hydrochloride, EP, AR
Catalogue No.	VQ-047286
CAS Number	1185-53-1
IUPAC name	2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride
Molecular formula	C₄H₁₂ClNO₃
Molecular weight	157.59 g/mol
Exact mass	157.0506
Grade	EP / AR
HSN code	29221990
InChIKey	QKNYBSVHEMOAJP-UHFFFAOYSA-N
SMILES	C(C(CO)(CO)N)O.Cl
PubChem CID	93573

Physical properties
Physical form	Other
H-bond donors / acceptors	5 / 4
TPSA	86.7 Å²
Synonyms	Tris(hydroxymethyl)aminomethane hydrochloride, Tromethamine hydrochloride, 2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride, TRIS HCl, Tris-HCl, Trometamol hydrochloride, Trizma hydrochloride, Tromethamine HCl, 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride, Tris chloride, Tris hydrochloride buffer, 2-Amino-2-hydroxymethyl-1,3-propanediol hydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 1185-53-1

Tris hydrochloride, 98%+

CAS: 1185-53-1
Formula: C₄H₁₂ClNO₃
MW: 157.59 g/mol

VQ-003141

Cell Culture

Tris hydrochloride, cell culture tested

CAS: 1185-53-1
Formula: C₄H₁₂ClNO₃
MW: 157.59 g/mol

VQ-046264

Molecular Biology

Tris hydrochloride, for molecular biology, 99%+

CAS: 1185-53-1
Formula: C₄H₁₂ClNO₃
MW: 157.59 g/mol

VQ-003433

AR

Tris hydrochloride, GR 99%+

CAS: 1185-53-1
Formula: C₄H₁₂ClNO₃
MW: 157.59 g/mol

VQ-003142

Frequently asked questions

What is the CAS number of Tris hydrochloride, EP, AR?

The CAS Registry Number of Tris hydrochloride, EP, AR is 1185-53-1. It is also known as Tris(hydroxymethyl)aminomethane hydrochloride, Tromethamine hydrochloride, 2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride.

What is the molecular formula and molecular weight of Tris hydrochloride, EP, AR?

Tris hydrochloride, EP, AR has the molecular formula C4H12ClNO3 and a molecular weight of 157.59 g/mol.

Which grade and pack sizes of Tris hydrochloride, EP, AR can I order?

We supply Tris hydrochloride, EP, AR in EP / AR grade, in 100 g, 500 g, 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tris hydrochloride, EP, AR?

Yes. Every lot of Tris hydrochloride, EP, AR is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tris hydrochloride, EP, AR be shipped internationally?

Yes. Tris hydrochloride, EP, AR is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.