Trofinetide

Name: Trofinetide
Brand: Vaqora Chemicals
SKU: VQ-028552

About Trofinetide

Listed under CAS 853400-76-7, Trofinetide is a stable isotope labelled analogue related to Trofinetide available from Vaqora Chemicals. The compound has the formula C13H21N3O6, corresponding to a molecular weight of 315.32 g/mol. The IUPAC name is (2S)-2-[[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidine-2-carbonyl]amino]pentanedioic acid. Alternative names: NNZ-2566 and ACP-2566.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Trofinetide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Trofinetide

View every impurity, metabolite and intermediate we list for Trofinetide.

Trofinetide impurities

Specifications & identifiers

Chemical identifiers
Product name	Trofinetide
Catalogue No.	VQ-028552
CAS Number	853400-76-7
IUPAC name	(2S)-2-[[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidine-2-carbonyl]amino]pentanedioic acid
Molecular formula	C₁₃H₂₁N₃O₆
Molecular weight	315.32 g/mol
Exact mass	315.143
Grade	Reference Standard
HSN code	38229090
InChIKey	BUSXWGRAOZQTEY-SDBXPKJASA-N
SMILES	C[C@]1(CCCN1C(=O)CN)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID	11318905

Physical properties
Physical form	Solid
LogP (XLogP3)	-3.9
H-bond donors / acceptors	4 / 7
TPSA	150 Å²
Synonyms	NNZ-2566, ACP-2566, L-Glutamic acid, glycyl-2-methyl-L-prolyl-, (2S)-2-(((2S)-1-(2-aminoacetyl)-2-methylpyrrolidine-2-carbonyl)amino)pentanedioic acid, (2S)-2-(((2S)-1-(2-aminoacetyl)-2-methylpyrrolidin-2-yl)formamido)pentanedioic acid, Glycyl-2-methyl-L-prolyl-L-glutamic acid, Trofinetide(NNZ2566), NNZ 2566, glycyl-L-2-methylprolyl-L-glutamic acid, (S)-2-((S)-1-(2-Aminoacetyl)-2-methylpyrrolidine-2-carboxamido)pentanedioic acid, ((S)-1-glycyl-2-methylpyrrolidine-2-carbonyl)-L-glutamic acid, Glutamic acid, glycyl-prolyl-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Trofinetide?

The CAS Registry Number of Trofinetide is 853400-76-7. It is also known as NNZ-2566, ACP-2566, L-Glutamic acid, glycyl-2-methyl-L-prolyl-.

What is the molecular formula and molecular weight of Trofinetide?

Trofinetide has the molecular formula C13H21N3O6 and a molecular weight of 315.32 g/mol. Its IUPAC name is (2S)-2-[[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidine-2-carbonyl]amino]pentanedioic acid.

What is Trofinetide used for?

Trofinetide is supplied as a characterised reference material related to Trofinetide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Trofinetide can I order?

We supply Trofinetide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Trofinetide?

Yes. Every lot of Trofinetide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Trofinetide be shipped internationally?

Yes. We export Trofinetide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.