Cortisone 21-succinate

About Cortisone 21-succinate

Cortisone 21-succinate is an impurity of Hydrocortisone carrying the CAS registry number 10215-75-5. The compound has the formula C25H32O8, corresponding to a molecular weight of 460.5 g/mol. It is also known as Cortisone 21-Hemisuccinate.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Hydrocortisone impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Hydrocortisone

View every impurity, metabolite and intermediate we list for Hydrocortisone.

Hydrocortisone impurities

Specifications & identifiers

Chemical identifiers
Product name	Cortisone 21-succinate
Catalogue No.	VQ-031097
CAS Number	10215-75-5
IUPAC name	4-[2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid
Molecular formula	C₂₅H₃₂O₈
Molecular weight	460.5 g/mol
Exact mass	460.2097
Grade	Reference Standard
HSN code	38229090
InChIKey	WVSVAJGDZIWYBX-WFLBVZAHSA-N
SMILES	C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CC[C@@]4(C(=O)COC(=O)CCC(=O)O)O)C
PubChem CID	11954172

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	2 / 8
TPSA	135 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cortisone 21-succinate?

The CAS Registry Number of Cortisone 21-succinate is 10215-75-5. It is also known as Cortisone 21-Hemisuccinate, 17,21-Dihydroxypregn-4-ene-3,11,20-trione 21-(hydrogensuccinate), 21-(3-Carboxy-1-oxopropoxy)-17-hydroxypregn-4-ene-3,11,20-trione.

What is the molecular formula and molecular weight of Cortisone 21-succinate?

Cortisone 21-succinate has the molecular formula C25H32O8 and a molecular weight of 460.5 g/mol.

What is Cortisone 21-succinate used for?

Cortisone 21-succinate is supplied as a characterised reference material related to Hydrocortisone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cortisone 21-succinate can I order?

We supply Cortisone 21-succinate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cortisone 21-succinate?

Yes. Every lot of Cortisone 21-succinate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cortisone 21-succinate be shipped internationally?

Yes. We export Cortisone 21-succinate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.