Acetyl Clozapine

About Acetyl Clozapine

Acetyl Clozapine is an impurity of Clozapine carrying the CAS registry number 1025951-76-1. Its molecular formula is C20H21ClN4O and its molecular weight is 368.9 g/mol. Its systematic (IUPAC) name is 1-[3-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzodiazepin-11-yl]ethanone. Alternative names: N-Acetyl clozapine and Clozapine, N-acetyl-.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Clozapine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Clozapine

View every impurity, metabolite and intermediate we list for Clozapine.

Clozapine impurities

Specifications & identifiers

Chemical identifiers
Product name	Acetyl Clozapine
Catalogue No.	VQ-035231
CAS Number	1025951-76-1
IUPAC name	1-[3-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzodiazepin-11-yl]ethanone
Molecular formula	C₂₀H₂₁ClN₄O
Molecular weight	368.9 g/mol
Exact mass	368.1404
Grade	Reference Standard
HSN code	38229090
InChIKey	RFOTYXUYVJKUSY-UHFFFAOYSA-N
SMILES	CC(=O)N1C2=C(C=C(C=C2)Cl)N=C(C3=CC=CC=C31)N4CCN(CC4)C
PubChem CID	10451705

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	0 / 3
TPSA	39.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Acetyl Clozapine?

The CAS Registry Number of Acetyl Clozapine is 1025951-76-1. It is also known as N-Acetyl clozapine, 1-(8-Chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-5-yl)ethanone, Clozapine, N-acetyl-.

What is the molecular formula and molecular weight of Acetyl Clozapine?

Acetyl Clozapine has the molecular formula C20H21ClN4O and a molecular weight of 368.9 g/mol. Its IUPAC name is 1-[3-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzodiazepin-11-yl]ethanone.

What is Acetyl Clozapine used for?

Acetyl Clozapine is supplied as a characterised reference material related to Clozapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Acetyl Clozapine can I order?

We supply Acetyl Clozapine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Acetyl Clozapine?

Yes. Every lot of Acetyl Clozapine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Acetyl Clozapine be shipped internationally?

Yes. We export Acetyl Clozapine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.