Ruxolitinib Phosphate

Name: Ruxolitinib Phosphate
Brand: Vaqora Chemicals
SKU: VQ-007735

About Ruxolitinib Phosphate

Ruxolitinib Phosphate (CAS 1092939-17-7) is a high-purity reference standard of Ruxolitinib offered by Vaqora Chemicals. With the molecular formula C17H21N6O4P, it has a molar mass of 404.4 g/mol. Systematically, it is named (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile. Phosphoric acid. It is also known as INC 424 phosphate or INCB 018424 phosphate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Ruxolitinib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ruxolitinib Phosphate is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Ruxolitinib

View every impurity, metabolite and intermediate we list for Ruxolitinib.

Ruxolitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ruxolitinib Phosphate
Catalogue No.	VQ-007735
CAS Number	1092939-17-7
Other CAS	941678-49-5, 2803478-47-7
IUPAC name	(3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;phosphoric acid
Molecular formula	C₁₇H₂₁N₆O₄P
Molecular weight	404.4 g/mol
Exact mass	404.1362
Grade	Reference Standard
HSN code	38229090
InChIKey	JFMWPOCYMYGEDM-XFULWGLBSA-N
SMILES	C1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O
PubChem CID	25127112

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 8
TPSA	161 Å²
Synonyms	INC 424 phosphate, INCB 018424 phosphate, Jakafi, Jakavi, ruxolitinib monophosphate, ruxolitinib (as phosphate), INCB-018424 phosphate, Ruxolitinib (phosphate), Ruxolitinib phosphate salt, Opzelura (TN), 1092939-17-7 (phosphate), Jakafi (TN)

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P270, P273, P280, P301 + P316, P301 + P317, P318, P319, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ruxolitinib Phosphate?

The CAS Registry Number of Ruxolitinib Phosphate is 1092939-17-7. It is also known as INC 424 phosphate, INCB 018424 phosphate, Jakafi.

What is the molecular formula and molecular weight of Ruxolitinib Phosphate?

Ruxolitinib Phosphate has the molecular formula C17H21N6O4P and a molecular weight of 404.4 g/mol.

What is Ruxolitinib Phosphate used for?

Ruxolitinib Phosphate is supplied as a characterised reference material related to Ruxolitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ruxolitinib Phosphate can I order?

We supply Ruxolitinib Phosphate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ruxolitinib Phosphate?

Yes. Every lot of Ruxolitinib Phosphate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ruxolitinib Phosphate be shipped internationally?

Yes. Ruxolitinib Phosphate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.