Ruxolitinib Metabolite 1 (Diastereomeric Mixt… 1092973-94-8

About Ruxolitinib Metabolite 1 (Diastereomeric Mixture)

Ruxolitinib Metabolite 1 (Diastereomeric Mixture) is a metabolite or degradation product of Ruxolitinib carrying the CAS registry number 1092973-94-8, specified at 97.8% purity. Formula C17H18N6O, molecular weight 322.4 g/mol. Its systematic (IUPAC) name is (3R)-3-(3-hydroxycyclopentyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile. Alternative names: Ruxolitinib Metabolite 1 and Ruxolitinib metabolite M7.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Ruxolitinib, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ruxolitinib Metabolite 1 (Diastereomeric Mixture) is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Ruxolitinib

View every impurity, metabolite and intermediate we list for Ruxolitinib.

Ruxolitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ruxolitinib Metabolite 1 (Diastereomeric Mixture)
Catalogue No.	VQ-007255
CAS Number	1092973-94-8
IUPAC name	(3R)-3-(3-hydroxycyclopentyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile
Molecular formula	C₁₇H₁₈N₆O
Molecular weight	322.4 g/mol
Exact mass	322.1542
Grade	Reference Standard
Purity / assay	97.8%
HSN code	38229090
InChIKey	PEDGDCYQFZPRCX-ABIUDSBCSA-N
SMILES	C1CC(CC1[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3)O
PubChem CID	73425520

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	2 / 5
TPSA	103 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ruxolitinib Metabolite 1 (Diastereomeric Mixture)?

The CAS Registry Number of Ruxolitinib Metabolite 1 (Diastereomeric Mixture) is 1092973-94-8. It is also known as β-(3-Hydroxycyclopentyl)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile, Ruxolitinib Metabolite 1, Ruxolitinib metabolite M7.

What is the molecular formula and molecular weight of Ruxolitinib Metabolite 1 (Diastereomeric Mixture)?

Ruxolitinib Metabolite 1 (Diastereomeric Mixture) has the molecular formula C17H18N6O and a molecular weight of 322.4 g/mol. Its IUPAC name is (3R)-3-(3-hydroxycyclopentyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile.

What is Ruxolitinib Metabolite 1 (Diastereomeric Mixture) used for?

Ruxolitinib Metabolite 1 (Diastereomeric Mixture) is supplied as a characterised reference material related to Ruxolitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ruxolitinib Metabolite 1 (Diastereomeric Mixture) can I order?

We supply Ruxolitinib Metabolite 1 (Diastereomeric Mixture) in Reference Standard (97.8%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ruxolitinib Metabolite 1 (Diastereomeric Mixture)?

Yes. Every lot of Ruxolitinib Metabolite 1 (Diastereomeric Mixture) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ruxolitinib Metabolite 1 (Diastereomeric Mixture) be shipped internationally?

Yes. We export Ruxolitinib Metabolite 1 (Diastereomeric Mixture) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.