Diltiazem EP Impurity A

About Diltiazem EP Impurity A

Diltiazem EP Impurity A is a pharmacopeial impurity of Diltiazem carrying the CAS registry number 111188-71-7. The compound has the formula C22H26N2O4S, corresponding to a molecular weight of 414.5 g/mol. Systematically, it is named [(2R,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate. Common synonyms include Diltiazem EP Impurity A (Free Base) and Diltiazem - Impurity A.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Diltiazem impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Diltiazem

View every impurity, metabolite and intermediate we list for Diltiazem.

Diltiazem impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Diltiazem EP Impurity A
Catalogue No.	VQ-025322
CAS Number	111188-71-7
IUPAC name	[(2R,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate
Molecular formula	C₂₂H₂₆N₂O₄S
Molecular weight	414.5 g/mol
Exact mass	414.1613
Grade	Reference Standard
HSN code	38229090
InChIKey	HSUGRBWQSSZJOP-NHCUHLMSSA-N
SMILES	CC(=O)O[C@@H]1[C@H](SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC
PubChem CID	978317

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	0 / 6
TPSA	84.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Diltiazem EP Impurity A?

The CAS Registry Number of Diltiazem EP Impurity A is 111188-71-7. It is also known as Diltiazem EP Impurity A (Free Base), Diltiazem - Impurity A.

What is the molecular formula and molecular weight of Diltiazem EP Impurity A?

Diltiazem EP Impurity A has the molecular formula C22H26N2O4S and a molecular weight of 414.5 g/mol. Its IUPAC name is [(2R,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate.

What is Diltiazem EP Impurity A used for?

Diltiazem EP Impurity A is supplied as a characterised reference material related to Diltiazem. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diltiazem EP Impurity A can I order?

We supply Diltiazem EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diltiazem EP Impurity A?

Yes. Every lot of Diltiazem EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diltiazem EP Impurity A be shipped internationally?

Yes. We export Diltiazem EP Impurity A worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.