Donepezil-d5

Name: Donepezil-d5
Brand: Vaqora Chemicals
SKU: VQ-043403

About Donepezil-d5

Listed under CAS 1128086-25-8, Donepezil-d5 is a stable isotope labelled analogue related to Donepezil available from Vaqora Chemicals. Its molecular formula is C24H29NO3 and its molecular weight is 384.5 g/mol. The IUPAC name is 5,6-dimethoxy-2-[[1-[(2,3,4,5,6-pentadeuteriophenyl)methyl]piperidin-4-yl]methyl]-2,3-dihydroinden-1-one. Common synonyms include TMIJ-0120.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Donepezil and related analytes in bioanalytical, pharmacokinetic and impurity studies. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Donepezil-d5 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Donepezil

View every impurity, metabolite and intermediate we list for Donepezil.

Donepezil impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Donepezil-d5
Catalogue No.	VQ-043403
CAS Number	1128086-25-8
IUPAC name	5,6-dimethoxy-2-[[1-[(2,3,4,5,6-pentadeuteriophenyl)methyl]piperidin-4-yl]methyl]-2,3-dihydroinden-1-one
Molecular formula	C₂₄H₂₉NO₃
Molecular weight	384.5 g/mol
Exact mass	384.2461
Grade	Reference Standard
HSN code	38229090
InChIKey	ADEBPBSSDYVVLD-DKFMXDSJSA-N
SMILES	[2H]C1=C(C(=C(C(=C1[2H])[2H])CN2CCC(CC2)CC3CC4=CC(=C(C=C4C3=O)OC)OC)[2H])[2H]
PubChem CID	46241038

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	0 / 4
TPSA	38.8 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Donepezil-d5?

The CAS Registry Number of Donepezil-d5 is 1128086-25-8. It is also known as TMIJ-0120.

What is the molecular formula and molecular weight of Donepezil-d5?

Donepezil-d5 has the molecular formula C24H29NO3 and a molecular weight of 384.5 g/mol. Its IUPAC name is 5,6-dimethoxy-2-[[1-[(2,3,4,5,6-pentadeuteriophenyl)methyl]piperidin-4-yl]methyl]-2,3-dihydroinden-1-one.

What is Donepezil-d5 used for?

Donepezil-d5 is supplied as a characterised reference material related to Donepezil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Donepezil-d5 can I order?

We supply Donepezil-d5 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Donepezil-d5?

Yes. Every lot of Donepezil-d5 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Donepezil-d5 be shipped internationally?

Yes. We export Donepezil-d5 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.