Sorafenib-d3

Name: Sorafenib-d3
Brand: Vaqora Chemicals
SKU: VQ-028092

About Sorafenib-d3

Sorafenib-d3 is a stable isotope labelled analogue related to Sorafenib carrying the CAS registry number 1130115-44-4. Formula C21H16ClF3N4O3, molecular weight 467.8 g/mol. Its systematic (IUPAC) name is 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-(trideuteriomethyl)pyridine-2-carboxamide. Common synonyms include d3-sorafenib and Sorafenib, Free Base.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Sorafenib-d3 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Sorafenib

View every impurity, metabolite and intermediate we list for Sorafenib.

Sorafenib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Sorafenib-d3
Catalogue No.	VQ-028092
CAS Number	1130115-44-4
IUPAC name	4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-(trideuteriomethyl)pyridine-2-carboxamide
Molecular formula	C₂₁H₁₆ClF₃N₄O₃
Molecular weight	467.8 g/mol
Exact mass	467.1051
Grade	Reference Standard
HSN code	38229090
InChIKey	MLDQJTXFUGDVEO-FIBGUPNXSA-N
SMILES	[2H]C([2H])([2H])NC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F
PubChem CID	25191001

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	3 / 7
TPSA	92.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sorafenib-d3?

The CAS Registry Number of Sorafenib-d3 is 1130115-44-4. It is also known as 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-(methyl-d3)picolinamide, d3-sorafenib, Sorafenib, Free Base.

What is the molecular formula and molecular weight of Sorafenib-d3?

Sorafenib-d3 has the molecular formula C21H16ClF3N4O3 and a molecular weight of 467.8 g/mol. Its IUPAC name is 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-(trideuteriomethyl)pyridine-2-carboxamide.

What is Sorafenib-d3 used for?

Sorafenib-d3 is supplied as a characterised reference material related to Sorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sorafenib-d3 can I order?

We supply Sorafenib-d3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sorafenib-d3?

Yes. Every lot of Sorafenib-d3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sorafenib-d3 be shipped internationally?

Yes. We export Sorafenib-d3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.