Ketorolac EP Impurity B

About Ketorolac EP Impurity B

Ketorolac EP Impurity B is a pharmacopeial impurity of Ketorolac carrying the CAS registry number 113502-52-6. Formula C14H11NO2, molecular weight 225.24 g/mol. Systematically, it is named 5-benzoyl-2,3-dihydropyrrolizin-1-one. It is also known as (Ketorolac USP RC C) or 5-Benzoyl-2,3-dihydro-1H-pyrrolizin-1-one.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Ketorolac to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 5 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Ketorolac

View every impurity, metabolite and intermediate we list for Ketorolac.

Ketorolac impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ketorolac EP Impurity B
Catalogue No.	VQ-006439
CAS Number	113502-52-6
IUPAC name	5-benzoyl-2,3-dihydropyrrolizin-1-one
Molecular formula	C₁₄H₁₁NO₂
Molecular weight	225.24 g/mol
Exact mass	225.079
Grade	Reference Standard
HSN code	38229090
InChIKey	NFKBMHXYCKRXPQ-UHFFFAOYSA-N
SMILES	C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)C1=O
PubChem CID	57357361

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	0 / 2
TPSA	39.1 Å²
Synonyms	(Ketorolac USP RC C), 5-Benzoyl-2,3-dihydro-1H-pyrrolizin-1-one, 1-Keto Ketorolac, Ketorolac 1-Keto Analogue, Ketorolac USP Related Compound C, Ketorolac 1-Keto, 1H-Pyrrolizin-1-one, 5-benzoyl-2,3-dihydro-, Ketorolac tromethamine impurity, ketorolac 1-keto analog-(USP), Ketorolac trometamol specified impurity B, 1-Keto-ketorolac, 5-benzoyl-2,3-dihydro-pyrrolizin-1-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ketorolac EP Impurity B?

The CAS Registry Number of Ketorolac EP Impurity B is 113502-52-6. It is also known as (Ketorolac USP RC C), 5-Benzoyl-2,3-dihydro-1H-pyrrolizin-1-one, 1-Keto Ketorolac.

What is the molecular formula and molecular weight of Ketorolac EP Impurity B?

Ketorolac EP Impurity B has the molecular formula C14H11NO2 and a molecular weight of 225.24 g/mol. Its IUPAC name is 5-benzoyl-2,3-dihydropyrrolizin-1-one.

What is Ketorolac EP Impurity B used for?

Ketorolac EP Impurity B is supplied as a characterised reference material related to Ketorolac. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ketorolac EP Impurity B can I order?

We supply Ketorolac EP Impurity B in Reference Standard grade, in 5 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ketorolac EP Impurity B?

Yes. Every lot of Ketorolac EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ketorolac EP Impurity B be shipped internationally?

Yes. Ketorolac EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.