Neratinib Impurity 4

Name: Neratinib Impurity 4
Brand: Vaqora Chemicals
SKU: VQ-005350

About Neratinib Impurity 4

Listed under CAS 1144516-19-7, Neratinib Impurity 4 is an impurity of Neratinib available from Vaqora Chemicals, specified at 99% purity. With the molecular formula C28H25ClN6O4, it has a molar mass of 545.0 g/mol. Systematically, it is named N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-N',N'-dimethyloxamide. Common synonyms include Neratinib Impurity 13.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Neratinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Neratinib

View every impurity, metabolite and intermediate we list for Neratinib.

Neratinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Neratinib Impurity 4
Catalogue No.	VQ-005350
CAS Number	1144516-19-7
IUPAC name	N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-N',N'-dimethyloxamide
Molecular formula	C₂₈H₂₅ClN₆O₄
Molecular weight	545 g/mol
Exact mass	544.1626
Grade	Reference Standard
Purity / assay	99%
HSN code	38229090
InChIKey	WZFWLTTUNBUKLD-UHFFFAOYSA-N
SMILES	CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C(=O)N(C)C
PubChem CID	25267997

Physical properties
Physical form	Solid
LogP (XLogP3)	4.5
H-bond donors / acceptors	2 / 8
TPSA	129 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Neratinib Impurity 4?

The CAS Registry Number of Neratinib Impurity 4 is 1144516-19-7. It is also known as Neratinib Impurity 13.

What is the molecular formula and molecular weight of Neratinib Impurity 4?

Neratinib Impurity 4 has the molecular formula C28H25ClN6O4 and a molecular weight of 545 g/mol. Its IUPAC name is N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-N',N'-dimethyloxamide.

What is Neratinib Impurity 4 used for?

Neratinib Impurity 4 is supplied as a characterised reference material related to Neratinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Neratinib Impurity 4 can I order?

We supply Neratinib Impurity 4 in Reference Standard (99%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Neratinib Impurity 4?

Yes. Every lot of Neratinib Impurity 4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Neratinib Impurity 4 be shipped internationally?

Yes. We export Neratinib Impurity 4 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.