Meclizine N-Oxide

Name: Meclizine N-Oxide
Brand: Vaqora Chemicals
SKU: VQ-026577

About Meclizine N-Oxide

Vaqora Chemicals supplies Meclizine N-Oxide, a metabolite or degradation product of Meclizine registered under CAS number 114624-69-0. With the molecular formula C25H27ClN2O, it has a molar mass of 406.9 g/mol. Systematically, it is named 4-[(4-chlorophenyl)-phenylmethyl]-1-[(3-methylphenyl)methyl]-1-oxidopiperazin-1-ium. It is also known as Meclozine N-Oxide or Meclizine N-Oxide (N4-Oxide).

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Meclizine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Meclizine

View every impurity, metabolite and intermediate we list for Meclizine.

Meclizine impurities

Specifications & identifiers

Chemical identifiers
Product name	Meclizine N-Oxide
Catalogue No.	VQ-026577
CAS Number	114624-69-0
IUPAC name	4-[(4-chlorophenyl)-phenylmethyl]-1-[(3-methylphenyl)methyl]-1-oxidopiperazin-1-ium
Molecular formula	C₂₅H₂₇ClN₂O
Molecular weight	406.9 g/mol
Exact mass	406.1812
Grade	Reference Standard
HSN code	38229090
InChIKey	NDTIJUDMDNMOFC-UHFFFAOYSA-N
SMILES	CC1=CC(=CC=C1)C[N+]2(CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl)[O-]
PubChem CID	54105930

Physical properties
Physical form	Solid
LogP (XLogP3)	5.2
H-bond donors / acceptors	0 / 2
TPSA	21.3 Å²
Synonyms	Meclozine N-Oxide, 4-((4-Chlorophenyl)(phenyl)methyl)-1-(3-methylbenzyl)piperazine 1-Oxide, Meclizine N-Oxide (N4-Oxide), Meclizine N1-Oxide, 1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)-methyl]- piperazine-N4-oxide, 4-[(4-Chlorophenyl)(phenyl)methyl]-1-[(3-methylphenyl)methyl]-1-oxo-1lambda~5~-piperazine, Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-, 4-oxide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Meclizine N-Oxide?

The CAS Registry Number of Meclizine N-Oxide is 114624-69-0. It is also known as Meclozine N-Oxide, 4-((4-Chlorophenyl)(phenyl)methyl)-1-(3-methylbenzyl)piperazine 1-Oxide, Meclizine N-Oxide (N4-Oxide).

What is the molecular formula and molecular weight of Meclizine N-Oxide?

Meclizine N-Oxide has the molecular formula C25H27ClN2O and a molecular weight of 406.9 g/mol. Its IUPAC name is 4-[(4-chlorophenyl)-phenylmethyl]-1-[(3-methylphenyl)methyl]-1-oxidopiperazin-1-ium.

What is Meclizine N-Oxide used for?

Meclizine N-Oxide is supplied as a characterised reference material related to Meclizine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Meclizine N-Oxide can I order?

We supply Meclizine N-Oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Meclizine N-Oxide?

Yes. Every lot of Meclizine N-Oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Meclizine N-Oxide be shipped internationally?

Yes. Meclizine N-Oxide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.