3,5-Diiodothyropropionic Acid

Name: 3,5-Diiodothyropropionic Acid
Brand: Vaqora Chemicals
SKU: VQ-012978

About 3,5-Diiodothyropropionic Acid

3,5-Diiodothyropropionic Acid (CAS 1158-10-7) is a process intermediate or related compound of Levothyroxine offered by Vaqora Chemicals. With the molecular formula C15H12I2O4, it has a molar mass of 510.06 g/mol. The IUPAC name is 3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid. Alternative names: Dipro and 3,5-Ditpa.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Levothyroxine, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 3,5-Diiodothyropropionic Acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Specifications & identifiers

Chemical identifiers
Product name	3,5-Diiodothyropropionic Acid
Catalogue No.	VQ-012978
CAS Number	1158-10-7
IUPAC name	3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid
Molecular formula	C₁₅H₁₂I₂O₄
Molecular weight	510.06 g/mol
Exact mass	509.8825
Grade	Reference Standard
InChIKey	WONYMNWUJVKVII-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1O)OC2=C(C=C(C=C2I)CCC(=O)O)I
PubChem CID	160565

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	2 / 4
TPSA	66.8 Å²
Synonyms	3-(4-(4-hydroxyphenoxy)-3,5-diiodophenyl)propanoic acid, 3,5-Diiodothyropropionic Acid, Dipro, 4-(4-Hydroxyphenoxy)-3,5-diiodobenzenepropanoic Acid, 3,5-Ditpa, Benzenepropanoic acid, 4-(4-hydroxyphenoxy)-3,5-diiodo-, DITPA cpd, 3,5-Diiodo-4-(4-hydroxyphenoxy)hydrocinnamic acid, 3,5-diiodothyropropanoic acid, 3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propionic acid, diiodothyropropionic-acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3,5-Diiodothyropropionic Acid?

The CAS Registry Number of 3,5-Diiodothyropropionic Acid is 1158-10-7. It is also known as 3-(4-(4-hydroxyphenoxy)-3,5-diiodophenyl)propanoic acid, 3,5-Diiodothyropropionic Acid, Dipro.

What is the molecular formula and molecular weight of 3,5-Diiodothyropropionic Acid?

3,5-Diiodothyropropionic Acid has the molecular formula C15H12I2O4 and a molecular weight of 510.06 g/mol. Its IUPAC name is 3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid.

What is 3,5-Diiodothyropropionic Acid used for?

3,5-Diiodothyropropionic Acid is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3,5-Diiodothyropropionic Acid can I order?

We supply 3,5-Diiodothyropropionic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3,5-Diiodothyropropionic Acid?

Yes. Every lot of 3,5-Diiodothyropropionic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3,5-Diiodothyropropionic Acid be shipped internationally?

Yes. 3,5-Diiodothyropropionic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.