(+)-Nebivolol

Name: (+)-Nebivolol
Brand: Vaqora Chemicals
SKU: VQ-026841

About (+)-Nebivolol

Vaqora Chemicals supplies (+)-Nebivolol, a high-purity reference standard of Nebivolol registered under CAS number 118457-15-1. Formula C22H25F2NO4, molecular weight 405.4 g/mol. Common synonyms include D-Nebivolol and (S,R,R,R)-Nebivolol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a reference sample of Nebivolol, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer (+)-Nebivolol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Nebivolol

View every impurity, metabolite and intermediate we list for Nebivolol.

Nebivolol impurities

Specifications & identifiers

Chemical identifiers
Product name	(+)-Nebivolol
Catalogue No.	VQ-026841
CAS Number	118457-15-1
IUPAC name	(1R)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-[[(2R)-2-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]amino]ethanol
Molecular formula	C₂₂H₂₅F₂NO₄
Molecular weight	405.4 g/mol
Exact mass	405.1752
Grade	Reference Standard
HSN code	38229090
InChIKey	KOHIRBRYDXPAMZ-YHBROIRLSA-N
SMILES	C1CC2=C(C=CC(=C2)F)O[C@H]1[C@@H](CNC[C@H]([C@@H]3CCC4=C(O3)C=CC(=C4)F)O)O
PubChem CID	189562

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	3 / 7
TPSA	71 Å²
Synonyms	D-Nebivolol, (S,R,R,R)-Nebivolol, Dexnebivolol, Bystolic, (+)-RRRS-nebivolol, (+)-(S,R,R,R)-nebivolol, (1R,1'R)-2,2'-iminobis{1-[(2R,2'S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol}, SRRR-Nebivolol, D-Nebivolol (SR,RR), SRRR and RSSS Nebivolol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (+)-Nebivolol?

The CAS Registry Number of (+)-Nebivolol is 118457-15-1. It is also known as D-Nebivolol, (S,R,R,R)-Nebivolol, Dexnebivolol.

What is the molecular formula and molecular weight of (+)-Nebivolol?

(+)-Nebivolol has the molecular formula C22H25F2NO4 and a molecular weight of 405.4 g/mol. Its IUPAC name is (1R)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-[[(2R)-2-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]amino]ethanol.

What is (+)-Nebivolol used for?

(+)-Nebivolol is supplied as a characterised reference material related to Nebivolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (+)-Nebivolol can I order?

We supply (+)-Nebivolol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (+)-Nebivolol?

Yes. Every lot of (+)-Nebivolol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (+)-Nebivolol be shipped internationally?

Yes. We export (+)-Nebivolol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.