2,2,2-Trifluoro-1-(2-fluoropyridin-3-yl)ethan… 1186608-79-6

About 2,2,2-Trifluoro-1-(2-fluoropyridin-3-yl)ethan-1-one

2,2,2-Trifluoro-1-(2-fluoropyridin-3-yl)ethan-1-one is a process intermediate or related compound of Riociguat carrying the CAS registry number 1186608-79-6. Its molecular formula is C7H3F4NO and its molecular weight is 193.1 g/mol. Systematically, it is named 2,2,2-trifluoro-1-(2-fluoro-3-pyridinyl)ethanone. Common synonyms include 2-Fluoro-3-trifluoroacetylpyridine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Process chemists and analysts use it when developing synthetic routes to Riociguat, tracking process-related impurities and validating analytical methods. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Riociguat

View every impurity, metabolite and intermediate we list for Riociguat.

Riociguat impurities

Specifications & identifiers

Chemical identifiers
Product name	2,2,2-Trifluoro-1-(2-fluoropyridin-3-yl)ethan-1-one
Catalogue No.	VQ-051300
CAS Number	1186608-79-6
IUPAC name	2,2,2-trifluoro-1-(2-fluoro-3-pyridinyl)ethanone
Molecular formula	C₇H₃F₄NO
Molecular weight	193.1 g/mol
Exact mass	193.0151
HSN code	2933
InChIKey	ZTKVVMLHWCELMA-UHFFFAOYSA-N
SMILES	C1=CC(=C(N=C1)F)C(=O)C(F)(F)F
PubChem CID	53416101

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	0 / 6
TPSA	30 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,2,2-Trifluoro-1-(2-fluoropyridin-3-yl)ethan-1-one?

The CAS Registry Number of 2,2,2-Trifluoro-1-(2-fluoropyridin-3-yl)ethan-1-one is 1186608-79-6. It is also known as 2-Fluoro-3-trifluoroacetylpyridine, 2,2,2-trifluoro-1-(2-fluoro-3-pyridyl)ethanone.

What is the molecular formula and molecular weight of 2,2,2-Trifluoro-1-(2-fluoropyridin-3-yl)ethan-1-one?

2,2,2-Trifluoro-1-(2-fluoropyridin-3-yl)ethan-1-one has the molecular formula C7H3F4NO and a molecular weight of 193.1 g/mol. Its IUPAC name is 2,2,2-trifluoro-1-(2-fluoro-3-pyridinyl)ethanone.

What is 2,2,2-Trifluoro-1-(2-fluoropyridin-3-yl)ethan-1-one used for?

2,2,2-Trifluoro-1-(2-fluoropyridin-3-yl)ethan-1-one is supplied as a characterised reference material related to Riociguat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,2,2-Trifluoro-1-(2-fluoropyridin-3-yl)ethan-1-one can I order?

We supply 2,2,2-Trifluoro-1-(2-fluoropyridin-3-yl)ethan-1-one, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,2,2-Trifluoro-1-(2-fluoropyridin-3-yl)ethan-1-one?

Yes. Every lot of 2,2,2-Trifluoro-1-(2-fluoropyridin-3-yl)ethan-1-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,2,2-Trifluoro-1-(2-fluoropyridin-3-yl)ethan-1-one be shipped internationally?

Yes. We export 2,2,2-Trifluoro-1-(2-fluoropyridin-3-yl)ethan-1-one worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.