rac-Ambrisentan-d3

Name: rac-Ambrisentan-d3
Brand: Vaqora Chemicals
SKU: VQ-043372

About rac-Ambrisentan-d3

rac-Ambrisentan-d3 (CAS 1189479-60-4) is a stable isotope labelled analogue related to Ambrisentan offered by Vaqora Chemicals. The compound has the formula C22H22N2O4, corresponding to a molecular weight of 381.4 g/mol. Systematically, it is named 2-(4,6-dimethylpyrimidin-2-yl)oxy-3,3-diphenyl-3-(trideuteriomethoxy)propanoic acid. Common synonyms include Ambrisentan-d3 and (+/-)-Ambrisentan-d3 (methoxy-d3).

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Ambrisentan and related analytes in bioanalytical, pharmacokinetic and impurity studies. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Ambrisentan

View every impurity, metabolite and intermediate we list for Ambrisentan.

Ambrisentan impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	rac-Ambrisentan-d3
Catalogue No.	VQ-043372
CAS Number	1189479-60-4
IUPAC name	2-(4,6-dimethylpyrimidin-2-yl)oxy-3,3-diphenyl-3-(trideuteriomethoxy)propanoic acid
Molecular formula	C₂₂H₂₂N₂O₄
Molecular weight	381.4 g/mol
Exact mass	381.1768
Grade	Reference Standard
HSN code	38229090
InChIKey	OUJTZYPIHDYQMC-HPRDVNIFSA-N
SMILES	[2H]C([2H])([2H])OC(C1=CC=CC=C1)(C2=CC=CC=C2)C(C(=O)O)OC3=NC(=CC(=N3)C)C
PubChem CID	46780134

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	1 / 6
TPSA	81.5 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of rac-Ambrisentan-d3?

The CAS Registry Number of rac-Ambrisentan-d3 is 1189479-60-4. It is also known as Ambrisentan-d3, (+/-)-Ambrisentan-d3 (methoxy-d3), 2-[(4,6-Dimethylpyrimidin-2-yl)oxy]-3-[(~2~H_3_)methyloxy]-3,3-diphenylpropanoic acid.

What is the molecular formula and molecular weight of rac-Ambrisentan-d3?

rac-Ambrisentan-d3 has the molecular formula C22H22N2O4 and a molecular weight of 381.4 g/mol. Its IUPAC name is 2-(4,6-dimethylpyrimidin-2-yl)oxy-3,3-diphenyl-3-(trideuteriomethoxy)propanoic acid.

What is rac-Ambrisentan-d3 used for?

rac-Ambrisentan-d3 is supplied as a characterised reference material related to Ambrisentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of rac-Ambrisentan-d3 can I order?

We supply rac-Ambrisentan-d3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with rac-Ambrisentan-d3?

Yes. Every lot of rac-Ambrisentan-d3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can rac-Ambrisentan-d3 be shipped internationally?

Yes. We export rac-Ambrisentan-d3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.