Pyrimethamine-d3

About Pyrimethamine-d3

Pyrimethamine-d3 is a stable isotope labelled analogue related to Pyrimethamine carrying the CAS registry number 1189936-99-9. Formula C12H13ClN4, molecular weight 251.73 g/mol. The IUPAC name is 5-(4-chlorophenyl)-6-(2,2,2-trideuterioethyl)pyrimidine-2,4-diamine. Common synonyms include TMID-1132.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Pyrimethamine-d3 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Pyrimethamine

View every impurity, metabolite and intermediate we list for Pyrimethamine.

Pyrimethamine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Pyrimethamine-d3
Catalogue No.	VQ-041143
CAS Number	1189936-99-9
IUPAC name	5-(4-chlorophenyl)-6-(2,2,2-trideuterioethyl)pyrimidine-2,4-diamine
Molecular formula	C₁₂H₁₃ClN₄
Molecular weight	251.73 g/mol
Exact mass	251.1017
Grade	Reference Standard
HSN code	38229090
InChIKey	WKSAUQYGYAYLPV-FIBGUPNXSA-N
SMILES	[2H]C([2H])([2H])CC1=C(C(=NC(=N1)N)N)C2=CC=C(C=C2)Cl
PubChem CID	45040307

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	2 / 4
TPSA	77.8 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Pyrimethamine-d3?

The CAS Registry Number of Pyrimethamine-d3 is 1189936-99-9. It is also known as TMID-1132.

What is the molecular formula and molecular weight of Pyrimethamine-d3?

Pyrimethamine-d3 has the molecular formula C12H13ClN4 and a molecular weight of 251.73 g/mol. Its IUPAC name is 5-(4-chlorophenyl)-6-(2,2,2-trideuterioethyl)pyrimidine-2,4-diamine.

What is Pyrimethamine-d3 used for?

Pyrimethamine-d3 is supplied as a characterised reference material related to Pyrimethamine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Pyrimethamine-d3 can I order?

We supply Pyrimethamine-d3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Pyrimethamine-d3?

Yes. Every lot of Pyrimethamine-d3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Pyrimethamine-d3 be shipped internationally?

Yes. We export Pyrimethamine-d3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.