Sofosbuvir

About Sofosbuvir

Sofosbuvir is a high-purity reference standard of Sofosbuvir carrying the CAS registry number 1190307-88-0. Formula C22H29FN3O9P, molecular weight 529.5 g/mol. It is also known as Sofosbuvir form 6 or PSI-7977.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Sofosbuvir standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Sofosbuvir in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Sofosbuvir

View every impurity, metabolite and intermediate we list for Sofosbuvir.

Sofosbuvir impurities

Specifications & identifiers

Chemical identifiers
Product name	Sofosbuvir
Catalogue No.	VQ-023773
CAS Number	1190307-88-0
IUPAC name	propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
Molecular formula	C₂₂H₂₉FN₃O₉P
Molecular weight	529.5 g/mol
Exact mass	529.1625
Grade	Reference Standard
HSN code	38229090
InChIKey	TTZHDVOVKQGIBA-IQWMDFIBSA-N
SMILES	C[C@@H](C(=O)OC(C)C)N[P@](=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3
PubChem CID	45375808

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	3 / 11
TPSA	153 Å²
Synonyms	Sofosbuvir form 6, PSI-7977, PSI 7977, Sovaldi Access, 7977, PSI, Psi-7977, gs-7977, Sofosbuvir (GS-7977), Sofosbuvir - Bio-X trade mark, SofosbuvirPSI7977GS-7977, EX-A389

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H372Causes damage to organs through prolonged or repeated exposure
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P264, P270, P301 + P317, P319, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sofosbuvir?

The CAS Registry Number of Sofosbuvir is 1190307-88-0. It is also known as Sofosbuvir form 6, PSI-7977, PSI 7977.

What is the molecular formula and molecular weight of Sofosbuvir?

Sofosbuvir has the molecular formula C22H29FN3O9P and a molecular weight of 529.5 g/mol. Its IUPAC name is propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate.

What is Sofosbuvir used for?

Sofosbuvir is supplied as a characterised reference material related to Sofosbuvir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sofosbuvir can I order?

We supply Sofosbuvir in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sofosbuvir?

Yes. Every lot of Sofosbuvir is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sofosbuvir be shipped internationally?

Yes. Sofosbuvir is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.