Desbenzyl Donepezil Hydrochloride

Name: Desbenzyl Donepezil Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-030276

About Desbenzyl Donepezil Hydrochloride

Desbenzyl Donepezil Hydrochloride (CAS 120013-39-0) is a metabolite or degradation product of Donepezil offered by Vaqora Chemicals. Its molecular formula is C17H24ClNO3 and its molecular weight is 325.8 g/mol. It is also known as Desbenzyl Donepezil or ACHE-IN-38 (hydrochloride).

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Donepezil, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Desbenzyl Donepezil Hydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Donepezil

View every impurity, metabolite and intermediate we list for Donepezil.

Donepezil impurities

Specifications & identifiers

Chemical identifiers
Product name	Desbenzyl Donepezil Hydrochloride
Catalogue No.	VQ-030276
CAS Number	120013-39-0
IUPAC name	5,6-dimethoxy-2-(piperidin-4-ylmethyl)-2,3-dihydroinden-1-one;hydrochloride
Molecular formula	C₁₇H₂₄ClNO₃
Molecular weight	325.8 g/mol
Exact mass	325.1445
Grade	Reference Standard
HSN code	38229090
InChIKey	WOZXDQQCMZIQEG-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(=C1)CC(C2=O)CC3CCNCC3)OC.Cl
PubChem CID	14553606

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 4
TPSA	47.6 Å²
Synonyms	Desbenzyl Donepezil, 4-((5,6-Dimethoxy-1-oxoindan-2-yl)methyl)piperidine hydrochloride, 4-[(5,6-Dimethoxy-1-oxoindan-2-yl)methyl]piperidine hydrochloride, 5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone hydrochloride, 5,6-dimethoxy-2-(piperidin-4-ylmethyl)-2,3-dihydro-1H-inden-1-one hydrochloride, 5,6-Dimethoxy-2-(4-piperidylmethyl)-1-indanone Hydrochloride, ACHE-IN-38 (hydrochloride), 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-, hydrochloride (1:1), Desbenzyl donezepil hydrochloride, 5,6-Dimethoxy-2-[(4-piperidyl)methyl]-1-indanone Hydrochloride, 5,6-Dimethoxy-2-(piperidin-4-ylmethyl) indan-1-one hydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Desbenzyl Donepezil Hydrochloride?

The CAS Registry Number of Desbenzyl Donepezil Hydrochloride is 120013-39-0. It is also known as Desbenzyl Donepezil, 4-((5,6-Dimethoxy-1-oxoindan-2-yl)methyl)piperidine hydrochloride, 4-[(5,6-Dimethoxy-1-oxoindan-2-yl)methyl]piperidine hydrochloride.

What is the molecular formula and molecular weight of Desbenzyl Donepezil Hydrochloride?

Desbenzyl Donepezil Hydrochloride has the molecular formula C17H24ClNO3 and a molecular weight of 325.8 g/mol.

What is Desbenzyl Donepezil Hydrochloride used for?

Desbenzyl Donepezil Hydrochloride is supplied as a characterised reference material related to Donepezil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Desbenzyl Donepezil Hydrochloride can I order?

We supply Desbenzyl Donepezil Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Desbenzyl Donepezil Hydrochloride?

Yes. Every lot of Desbenzyl Donepezil Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Desbenzyl Donepezil Hydrochloride be shipped internationally?

Yes. Desbenzyl Donepezil Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.