Anastrozole EP Impurity C

About Anastrozole EP Impurity C

Anastrozole EP Impurity C is a pharmacopeial impurity of Anastrozole carrying the CAS registry number 120511-84-4, specified at 85% purity. Its molecular formula is C15H17BrN2 and its molecular weight is 305.21 g/mol. Its systematic (IUPAC) name is 2-[3-(bromomethyl)-5-(2-cyanopropan-2-yl)phenyl]-2-methylpropanenitrile. Alternative names: 5-Bromomethyl Anastrozole and 3,5-Bis(1-cyano-1-methylethyl)benzyl bromide.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Anastrozole, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Anastrozole

View every impurity, metabolite and intermediate we list for Anastrozole.

Anastrozole impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Anastrozole EP Impurity C
Catalogue No.	VQ-006240
CAS Number	120511-84-4
IUPAC name	2-[3-(bromomethyl)-5-(2-cyanopropan-2-yl)phenyl]-2-methylpropanenitrile
Molecular formula	C₁₅H₁₇BrN₂
Molecular weight	305.21 g/mol
Exact mass	304.0575
Grade	Reference Standard
Purity / assay	85%
HSN code	38229090
InChIKey	IHXHGCDOJLOZML-UHFFFAOYSA-N
SMILES	CC(C)(C#N)C1=CC(=CC(=C1)CBr)C(C)(C)C#N
PubChem CID	11522359

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	0 / 2
TPSA	47.6 Å²
Synonyms	5-Bromomethyl Anastrozole, 5-(Bromomethyl)-α1,α1,α3,α3-tetramethyl-1,3-benzenediacetonitrile, 2,2'-(5-(Bromomethyl)-1,3-phenylene)bis(2-methylpropionitrile), a,a,a',a'-Tetramethyl-5-bromomethyl-1,3-benzenediacetonitrile, 2,2'-[5-(Bromomethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile), 3,5-Bis(1-cyano-1-methylethyl)benzyl bromide, 3,5-Bis(2-cyanoprop-2-yl)benzyl bromide, Anastrozole USP Related Compound D, 2,2'-(5-(Bromomethyl)-1,3-phenylene)bis(2-methylpropanenitrile), Anastrozole Impurity IV, 2-[3-(bromomethyl)-5-(1-cyano-1-methylethyl)phenyl]-2-methylpropanenitrile, 2,2-(5-(Bromomethyl)benzene-1,3-diyl)bis(2-methylpropanenitrile)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Anastrozole EP Impurity C?

The CAS Registry Number of Anastrozole EP Impurity C is 120511-84-4. It is also known as 5-Bromomethyl Anastrozole, 5-(Bromomethyl)-α1,α1,α3,α3-tetramethyl-1,3-benzenediacetonitrile, 2,2'-(5-(Bromomethyl)-1,3-phenylene)bis(2-methylpropionitrile).

What is the molecular formula and molecular weight of Anastrozole EP Impurity C?

Anastrozole EP Impurity C has the molecular formula C15H17BrN2 and a molecular weight of 305.21 g/mol. Its IUPAC name is 2-[3-(bromomethyl)-5-(2-cyanopropan-2-yl)phenyl]-2-methylpropanenitrile.

What is Anastrozole EP Impurity C used for?

Anastrozole EP Impurity C is supplied as a characterised reference material related to Anastrozole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Anastrozole EP Impurity C can I order?

We supply Anastrozole EP Impurity C in Reference Standard (85%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Anastrozole EP Impurity C?

Yes. Every lot of Anastrozole EP Impurity C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Anastrozole EP Impurity C be shipped internationally?

Yes. Anastrozole EP Impurity C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.